This article, based on a qualitative methodology that includes in-depth interviews with 85 migrant-smugglers who operate at the border between Mexico and the United States, addresses three research questions: do migrant-smugglers take part in organised crime? Are criminal groups involved in migrant smuggling? And are migrant-smugglers engaged in drug trafficking? It concludes that many smugglers have become part of organised crime groups but only after leaving the migrant-smuggling business; that criminal organisations do not help migrants to cross the border; and that migrant-smugglers do not carry drugs.Empirical evidence on the existence of ties between migrant smuggling and drug trafficking is scarce. However, official discourse and the media both emphasise that migrant smuggling is a business that has passed into the hands of organised crime and that migrants are exploited by traffickers who, in addition to charging them excessive fees, rob them, abandon them or require them to transport drugs. The connection between migrant smuggling and organised crime and the threat raised to national security have increased the legitimacy and urgency of the fight against illegal immigration, which has gone from consideration as a human rights issue to being understood as a matter of criminal justice and national security (Farrell and Fahy, 2009). Thus, the United Nations Protocol on migrant smuggling assumes that this is an increasingly sophisticated business operated by organised crime and requires governments to criminalise this activity (Gallagher, 2010: 94). The result has been the consolidation of border security policies in which undocumented migration, drug trafficking and terrorism are combatted with the same instruments.This article, based on in-depth interviews with 85 migrant-smugglers operating along the US-Mexico border, addresses three research questions: Do migrant-smugglers take part in organised crime? Are criminal groups involved in migrant smuggling? Are migrant-smugglers engaged in drug trafficking?First, the methodology is outlined and the sample is described; coyotaje is then defined. Next, the literature on the relationship between drug trafficking and migrant smuggling is reviewed and the extent to which migrant-smugglers are involved with organised crime is examined. The involvement of criminal groups in migrant smuggling is analysed, and, finally, migrant-smugglers' participation in drug trafficking is discussed.