Steatorrhea Following the Use of Antibiotics

Severe coagulation defect due to a dietary deficiency of vitamin K.

“…In high oral dosage mucosal damage occurs but parenterally administered neomycin does not have these effects. Merliss and Hoffman (1951) describe four cases of steatorrhoea associated with oral antibiotic therapy, including tetracycline, but there is no mention of any haemostatic defect occurring as a result and no biopsy data are given.…”

Steatorrhoea in the Adult

“…They may be important in the few cases where the steatorrhoea accompanies agammaglobulinaemia, or when the normal flor.a of the gut has been destroyed by a broad-spectrum antibiotic (Merliss and Hoffman, 1951). Whipple's disease should be classed as a collagen disease.…”

Inhibition of Several Antibiotics on D-Amino Acid Oxidase

“…However, subsequent studies revealed that the suppressions of the bacterial flora sensitive to the antibio tics were followed by the overgrowths of resistant bacterial flora (5,6) and that the altered intestinal bacterial flora also synthesized riboflavin (7). In addition, the reports of these investigators (1)(2)(3)(4) suggested that the manifes tation of the symptoms following administrations of antibiotics occurred much earlier than that following the feeding with riboflavin-deficient diets (8).…”