Steroids

Sherma, Joseph

doi:10.1201/9780203912430.ch30

Cited by 4 publications

(3 citation statements)

References 85 publications

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“…Alcoxysilanes, due to their multifunctionality (di- or trialcoxy-) could also create a continuous silica layer around single cellulose fibres [ 40 , 41 , 42 , 43 ]. However, if the modification procedure is right, the formation of siloxane bonds may be suppressed and the immobilisation of a silane monolayer on the cellulose surface is predominantly observed [ 41 , 42 , 43 ]. Based on SEM observation from Figure 5 , a multilayer of silica was not detected.…”

Section: Discussionmentioning

confidence: 99%

Chemical Modification of Cellulose Microfibres to Reinforce Poly(methyl methacrylate) Used for Dental Application

2020

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The mechanical properties of dental acrylic resins have to be improved in the case of a thin denture plate. This can be achieved by cellulose addition, playing the role of active filler. But to provide the excellent dispersion of cellulose microfibres within the hydrophobic polymer matrix, its surface has to be modified. Cellulose microfibres with average length from 8 to 30 μm were modified with octyltriethoxysilane and (3-methacryloxypropyl)methyldimethoxysilane. The latter also participated in the polymerisation reaction of methyl methacrylate. Dental composites were prepared following the general procedure provided by the supplier. The successful modification of the microfibres led to the improved compatibility of the cellulose and poly(methyl methacrylate). The fibres after modification were uniformly distributed within the matrix, resulting in the improved mechanical performance of obtained materials. Cellulose microfibres are good candidates for the dental materials to be used as the active filler. The simple and straightforward approach for the cellulose modifications with silanes provides good potential for its future practical application.

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Section: Discussionmentioning

confidence: 99%

Chemical Modification of Cellulose Microfibres to Reinforce Poly(methyl methacrylate) Used for Dental Application

2020

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“…Then the optical methods (UV/MS/NMR) or thin layer chromatography (TLC) methods were used to analyze the properties of these compounds. UV and TLC methods are relatively old methods [ 85 , 86 ], and currently mass spectrometry (MS) and nuclear magnetic resonance (NMR) methods are usually used to analyze the properties of compounds.…”

Section: Methodologies Of Screening Marine Antimicrobial Substancementioning

confidence: 99%

Screening of Marine Bioactive Antimicrobial Compounds for Plant Pathogens

Zhao

Chen

2021

Marine Drugs

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Plant diseases have been threatening food production. Controlling plant pathogens has become an important strategy to ensure food security. Although chemical control is an effective disease control strategy, its application is limited by many problems, such as environmental impact and pathogen resistance. In order to overcome these problems, it is necessary to develop more chemical reagents with new functional mechanisms. Due to their special living environment, marine organisms have produced a variety of bioactive compounds with novel structures, which have the potential to develop new fungicides. In the past two decades, screening marine bioactive compounds to inhibit plant pathogens has been a hot topic. In this review, we summarize the screening methods of marine active substances from plant pathogens, the identification of marine active substances from different sources, and the structure and antibacterial mechanism of marine active natural products. Finally, the application prospect of marine bioactive substances in plant disease control was prospected.

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“…Practical details of the TLC method was as described elsewhere. 11,12 A mixture of ethyl acetate and methanol (1:3 v/v) containing 0.25% v/v glacial acetic acid was used as the mobile phase. Lactose with a concentration of (1mg mL -1 ) in diluent solution (methanol: water (2:3 v/v)) was spotted as the reference standard.…”

Section: Methodsmentioning

confidence: 99%

Analytical Investigation of the Possible Chemical Interaction of Methyldopa with Some Reducing Carbohydrates Used as Pharmaceutical Excipients

2018

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Purpose: Assessment of drug substance and excipients compatibility is an important issue during pre-formulation studies as well as the quality control of pharmaceutical dosage forms. In this study, potential incompatibility between methyldopa and reducing excipients was evaluated using physicochemical methods.Methods: Dextrose and lactose (anhydrous & monohydrate) were selected as reducing carbohydrates. The initial incompatibility was studied with DSC and FTIR on binary mixtures with 1:1 mass ratio. Results were confirmed using HPLC studies coupled with mass spectrometry.Results: The DSC curves indicated the elimination of the melting endotherm of methyldopa in the binary mixtures. A new peak at 1719 cm-1 was observed in the FTIR spectra that can be attributed to the loss of type one amine functionality. The m/z of the proposed compound was observed in the mass spectra.Conclusion: The potential incompatibility of Methyldopa with reducing carbohydrates was established using physicochemical methods.

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Steroids

Cited by 4 publications

References 85 publications

Chemical Modification of Cellulose Microfibres to Reinforce Poly(methyl methacrylate) Used for Dental Application

Chemical Modification of Cellulose Microfibres to Reinforce Poly(methyl methacrylate) Used for Dental Application

Screening of Marine Bioactive Antimicrobial Compounds for Plant Pathogens

Analytical Investigation of the Possible Chemical Interaction of Methyldopa with Some Reducing Carbohydrates Used as Pharmaceutical Excipients

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