This study seeks to develop the infrastructure of the Gulf Electronic Scientific Research database (GESR), which depends on one of the integrated library systems that operate under the Machine readable cataloging (Henceforth, MARC21), The development of the database aims to optimize and expand the multi-language data display. As well as it enlarges databases reading resources of research systems in the Bibliographic Record MARC21, whether for basic search, advanced search, or specialized research. It also develops the capabilities of the fixed-length data field (008) to enhance the advanced search capabilities. The development system includes the expansion of crossing references to link the different forms of the main and added entries. The study aims at improving the application of RDA rules and the data display system according to the possibilities of the displaying form of the side sorting of the contents on the database website so that the lists of authors, title, keywords and biographies, Patents, institutions, and meetings. The research is based on the experimental analytical method, which depends on data analysis and processing through the integrated automated system, It presents the knowledge database as a unique system that combines the requirements of collecting and storing data availability and the technical work rules required by the MARC21 format. The researcher applied the analytical descriptive and the experimental approaches in order to identify the general and specific frameworks for the structure of the GESR database and to review the mechanisms for evaluating and developing the components of the integrated library system VTLS-VIRTUA.