2002
DOI: 10.1086/341858
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Strategies for Discovering Mechanisms: Schema Instantiation, Modular Subassembly, Forward/Backward Chaining

Abstract: Discovery proceeds in stages of construction, evaluation, and revision. Each of these stages is constrained by what is known or conjectured about what is being discovered. A new characterization of mechanism aids in specifying what is to be discovered when a mechanism is sought. Guidance in discovering mechanisms may be provided by the reasoning strategies of schema instantiation, modular subassembly, and forward/backward chaining. Examples are found in mechanisms in molecular biology, biochemistry, immunology… Show more

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Cited by 134 publications
(92 citation statements)
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“…Forward and backward chaining are reciprocal strategies for reasoning about one part of a decision on the basis of what is known or conjectured about other parts of the decision (Darden, 2002). Forward chaining uses the early stages of a decision to determine the types of entities and activities that are likely to be found downstream.…”
Section: System Modules and Interaction Mechanism Designmentioning
confidence: 99%
“…Forward and backward chaining are reciprocal strategies for reasoning about one part of a decision on the basis of what is known or conjectured about other parts of the decision (Darden, 2002). Forward chaining uses the early stages of a decision to determine the types of entities and activities that are likely to be found downstream.…”
Section: System Modules and Interaction Mechanism Designmentioning
confidence: 99%
“…By mechanistic reasoning, we mean that teachers must not only understand that a particular cause leads to a particular effect but also how this particular cause brings about this particular effect [38][39][40][41][42][43][44]. Russ and coauthors [38,39] adopt the term "chaining" [42,43] for describing how each stage of a mechanism "necessarily follows from the one before it and necessarily leads to the one after it," and consider chaining to be "strong evidence of mechanistic reasoning" [39]. In this perspective, the central components of mechanisms are activities (the "components of mechanisms that produce change") and entities (the things that engage in activities).…”
Section: B Mechanistic Reasoning About Energymentioning
confidence: 99%
“…Consequently, these constructs impact broadly on how we approach science and what constitutes a scientific explanation. The issue becomes especially acute for multi-level interdisciplinary approaches in the neurosciences, which seek to integrate information across disparate levels of organization and function, and associated levels of observation and analysis [11,24]. Neuroscience refers to the collection of disciplines concerned with the structure and function of the nervous system.…”
Section: Review Evolution Of Neuroarchitecture G G Berntson Et Al 69mentioning
confidence: 99%