Three-dimensional (3D) electronic systems enable higher integration densities compared to their 2D counterparts, a gain required to meet the demands of future exa-scale computing, cloud computing, big data systems, cognitive computing, mobile devices and other emerging technologies. Through-silicon vias (TSVs) open a pathway to integrate electrical connections for signaling and power delivery through the silicon (Si) carrier used in 3D-stacked microstructures. As a limitation, TSVs induce locally thermomechanical stress in the Si lattice due to a mismatch in the coefficients of thermal expansion between Si and the TSV-filling metals and therefore enforce temperature related expansion and shrinkage during the annealing cycle. This temperature-induced crowding and relaxation of the Si lattice in proximity of the TSV (called 'keep-out-zone' forbidden for active device positioning) can cause a variety of issues ranging from stress-induced device performance degradation, interfacial delamination or interconnect failures due to cracking of the bond or even of the entire Si microstructures at stress hotspots upon assembly or operation. Additionally also the interconnect structures induce stress that will overlap with the TSV induced stress