The appearance of strain localization (SL) in front of the crack tip is a factor that promotes transition toward the fatigue crack extension mode. Therefore, to predict fatigue crack extension behavior in case multiple modes occur, it is necessary to evaluate the degree of SL. In this study, the following simulations were performed on a single-crystal twinning-induced plasticity (TWIP) steel:(a) SL characterization by crystal plasticity finite element method (CPFEM) analysis of a smooth specimen under tension, (b) strain concentration (SC) characterization by EP-FEM analysis of a cracked specimen under tension, and (c) characterization of interaction results between SC and SL of a cracked specimen under tension by CPFEM analysis. A comparison of the above results found that the interaction between SC and SL was large for long cracks and a significant strain field, different from the Hutchinson, Rice, Rosengren (HRR) singular field, was formed in front of the crack tip. Therefore, a parameter was proposed to quantify the SL properties in a smooth specimen.Subsequently, a fracture-mechanics-like method was proposed in which the results of (b) and the introduced parameters control the results of (c).