2016
DOI: 10.1016/j.carbpol.2016.04.106
|View full text |Cite
|
Sign up to set email alerts
|

Structural characterization and antidiabetic activity of a glucopyranose-rich heteropolysaccharide from Catathelasma ventricosum

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
15
0

Year Published

2016
2016
2024
2024

Publication Types

Select...
9
1

Relationship

0
10

Authors

Journals

citations
Cited by 42 publications
(15 citation statements)
references
References 29 publications
0
15
0
Order By: Relevance
“…The different molecular weight of polysaccharides acquired from Ophiopogon japonicas (MW: 3.47, 6.746, 35.2, 124.3, and 324.6 kDa), Acaudina molpadioides (MW: 1614.1 kDa), and mulberry leaf (MW: 289) reduced hyperglycemia and hyperinsulinemia in STZ-induced diabetic mice. Polysaccharide triggers the PI3K/Akt signaling pathway through IRS1, PI3K-p85, and phosphorylated Akt develops insulin sensitivity [26,123,143] and improves diabetic-associated renal disease [144]. Moreover, treatment of these polysaccharides increased GLUT4 levels in pancreas and decreased glycogen synthase kinase-3 β levels in most of the cells.…”
Section: Mechanism Of Dietary Polysaccharides On Anti-diabetic Actmentioning
confidence: 99%
“…The different molecular weight of polysaccharides acquired from Ophiopogon japonicas (MW: 3.47, 6.746, 35.2, 124.3, and 324.6 kDa), Acaudina molpadioides (MW: 1614.1 kDa), and mulberry leaf (MW: 289) reduced hyperglycemia and hyperinsulinemia in STZ-induced diabetic mice. Polysaccharide triggers the PI3K/Akt signaling pathway through IRS1, PI3K-p85, and phosphorylated Akt develops insulin sensitivity [26,123,143] and improves diabetic-associated renal disease [144]. Moreover, treatment of these polysaccharides increased GLUT4 levels in pancreas and decreased glycogen synthase kinase-3 β levels in most of the cells.…”
Section: Mechanism Of Dietary Polysaccharides On Anti-diabetic Actmentioning
confidence: 99%
“…In an investigation of the relationship between structure and the reported antihyperglycemic effect of polysaccharides from Catathelasma ventricosum mushrooms, Liu et al [ 18 , 33 , 34 ], describe their isolation and characterization. The freeze-dried powdered mushrooms (200 g) were defatted and decolorized with 95% ethanol and the suspension was centrifuged.…”
Section: Isolation and Characterization Of Mushroom Polysaccharidementioning
confidence: 99%
“…A heteropolysaccharide with a molecular weight of 15 kDa was found to have hypoglycemic, and hypolipidemic activities on the streptozotocin-induced diabetic mouse, and the FBG level was reduced by 48.58% aer polysaccharides treatment (100 mg per kg per day), in comparison with the diabetic control. 31 Polysaccharide fraction from Opuntia dillenii Haw. fruits (200 mg per kg per day) could signicantly decrease FBG level by 34.4% using streptozotocininduced diabetic mouse model, compared with diabetic control rats.…”
Section: Effect Of Glp On the Fasting Blood Glucose Levels And Oral Gmentioning
confidence: 99%