Structural Effects on the Biodegradation of Aliphatic Polyesters

Mochizuki, Masahito; Hirami, Matsuo

doi:10.1002/(sici)1099-1581(199704)8:4<203::aid-pat627>3.0.co;2-3

Cited by 210 publications

(83 citation statements)

References 10 publications

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“…In nature, the degradation of PLA can be induced, for example, by thermal activation, biological activity (enzymes), oxidation, photolysis, or hydrolysis. 34,35 In this study, in which physiological conditions are simulated without the involvement of biological entities and other external factors (temperature, gases), hydrolysis is suggested to be the main phenomenon that can degrade PLA. This process, called hydrolytic degradation, relies on the polymer chain scission that occurs through the nonspecific cleavage of the ester bonds of the main chain.…”

Section: Discussionmentioning

confidence: 99%

Fast-degrading PLA/ORMOGLASS fibrous composite scaffold leads to a calcium-rich angiogenic environment

Sachot¹,

Roguska²,

Planell³

et al. 2017

IJN

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The success of scaffold implantation in acellular tissue engineering approaches relies on the ability of the material to interact properly with the biological environment. This behavior mainly depends on the design of the graft surface and, more precisely, on its capacity to biodegrade in a well-defined manner (nature of ions released, surface-to-volume ratio, dissolution profile of this release, rate of material resorption, and preservation of mechanical properties). The assessment of the biological behavior of temporary templates is therefore very important in tissue engineering, especially for composites, which usually exhibit complicated degradation behavior. Here, blended polylactic acid (PLA) calcium phosphate ORMOGLASS (organically modified glass) nanofibrous mats have been incubated up to 4 weeks in physiological simulated conditions, and their morphological, topographical, and chemical changes have been investigated. The results showed that a significant loss of inorganic phase occurred at the beginning of the immersion and the ORMOGLASS maintained a stable composition afterward throughout the degradation period. As a whole, the nanostructured scaffolds underwent fast and heterogeneous degradation. This study reveals that an angiogenic calcium-rich environment can be achieved through fast-degrading ORMOGLASS/PLA blended fibers, which seems to be an excellent alternative for guided bone regeneration.

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Section: Discussionmentioning

confidence: 99%

Fast-degrading PLA/ORMOGLASS fibrous composite scaffold leads to a calcium-rich angiogenic environment

Sachot¹,

Roguska²,

Planell³

et al. 2017

IJN

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“…After 7 days, the root canal dressing was removed as follows: flushing with 5 mL 5% NaOCl at [40][41][42][43][44][45][46][47][48][49][50] C; K-Flexofile 20 ISO (Dentsply Maillefer, Ballaigues, Switzerland) 1 mm short of the working length (WL); flushing with 5 mL 10% EDTA; flushing with 5 mL 5% NaOCl at [40][41][42][43][44][45][46][47][48][49][50] C; K-Flexofile 20 ISO 1 mm short of the WL; flushing with 5 mL 10% EDTA; K-Flexofile 20 ISO 1 mm short of the WL; final flush with 5 mL 10% EDTA for 2 min.…”

Section: Specimen Preparationmentioning

confidence: 99%

Microbial Leakage of Gutta-percha and Resilon™ Root Canal Filling Material: A Comparative Study Using a new Homogeneous Assay for Sequence Detection

et al. 2008

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The sealing ability of gutta-percha/sealer root canal filling was compared to a new thermoplastic synthetic polymer-based obturation material (Resilon TM ), using a microleakage model and a new sequence detection assay One Cut Event AmplificatioN (OCEAN TM ). Eighty-eight extracted human teeth, shaped with K-Files and the ProTaper Technique, were randomly assigned to four groups (n ¼ 22) and obturated in the apical 5 mm. Group R were obturated with the Resilon/Epiphany technique; group GP were obturated with guttapercha and Zinc oxide eugenoe sealer; group RCH and GPCH received calcium hydroxide intracanal medication before being obturated. Sterilized specimens were inoculated with Enterococcus faecalis and incubated in sterile medium for 47 days. DNA extracted from the specimens was amplified by PCR and then identified by the OCEAN technique. Samples obturated with Resilon root canal *Author to whom correspondence should be addressed. E-mail: dampasq@libero.it

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“…As shown in Figure 2 (a), degradation of pure PHB is complete at 300 ºC. The lower weight loss is an indication that the blends are thermally more stable than PHB over a wider temperature range [16,17,18]. Thermal degradation of pure PHB and PP/HMSPP basis occurs through one step, characterised by a single peak on Figure 2 All sugarcane bagasse foamed compositions exhibited tensile stress values higher than that one presented by PP/HMSPP polymeric base, proportionally on increasing bagasse contents.…”

Section: Phb Foamsmentioning

confidence: 99%

Development of Partially Biodegradable Foams From Pp/HMSPP Blends With Natural and Synthetic Polymers

Cardoso¹,

Scagliusi²,

Parra³

et al. 2018

Proceedings of the 4th Brazilian Conference on Composite Materials

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Polymers are used in various applications and in different industrial areas providing enormous quantities of wastes in environment. Among diverse components of residues in landfills are polymeric materials, including Polypropylene, which contribute with 20 to 30 % of total volume of solid residues. As polymeric materials are immune to microbial degradation, they remain in soil and in landfills as a semi-permanent residue. Environmental concerning in litter reduction is being directed to renewable polymers development for manufacturing of polymeric foams. Foamed polymers are considered future materials, with a wide range of applications; high density structural foams are specially used in civil construction, in replacement of metals, woods and concrete with a final purpose of reducing materials costs. At present development, it was possible the incorporation of PP/HMSPP polymeric matrix blends with sugarcane bagasse and PHB in structural foams production. Gamma radiation degradation, at 50, 100, 150, 200 and 500 kGy showed effective for biodegradability induction. Irradiated bagasse blends suffered surface erosion, in favor of water uptake and consequently, a higher biodegradation in bulk structure.

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Structural Effects on the Biodegradation of Aliphatic Polyesters

Cited by 210 publications

References 10 publications

Fast-degrading PLA/ORMOGLASS fibrous composite scaffold leads to a calcium-rich angiogenic environment

Fast-degrading PLA/ORMOGLASS fibrous composite scaffold leads to a calcium-rich angiogenic environment

Microbial Leakage of Gutta-percha and Resilon™ Root Canal Filling Material: A Comparative Study Using a new Homogeneous Assay for Sequence Detection

Development of Partially Biodegradable Foams From Pp/HMSPP Blends With Natural and Synthetic Polymers

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