Structures Involved in Acquisition and Performance of Visually Guided Movements in the Cat

Fabre, Mélanie; Buser, P

doi:10.1007/978-94-009-8225-3_20

Cited by 20 publications

(12 citation statements)

References 48 publications

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“…In addition, indirect evidence points to the switching of motor control from the corticospinal system to the cortico-rubrospinal system during motor learning. In the case of instrumental feeding reflexes in cats, it was shown that conditioning is impossible after a preliminary destruction of the ventrolateral nucleus of the thalamus (which presumably had interrupted the cerebello-cortical pathway), but if the reflex is conditioned, it persists even after the destruction of the ventrolateral nucleus ofthe thalamus (Fabre & Buser, 1980).…”

Section: Discussionmentioning

confidence: 99%

Enhanced Behavioral Recovery from Sensorimotor Cortex Lesions After Pyramidotomy in Adult Rats

et al. 2000

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Unilateral transection of the bulbar pyramid, performed before the ablation of the ipsilateral sensorimotor cortex, has been shown to facilitate the recovery of operantly conditioned reflexes and compensatory processes in rats. Such enhanced behaviorai recovery was absent when only the sensorimotor cortex was ablated. This phenomenon is explained by the switching of motor activity under the control of the cortico-rubrospinal system. Switching of the descending influences is accomplished through the following loop: cortico-rubrai projectionred nucleus-inferior olive-cerebellum-thalamuscerebral cortex. This suggests that a preliminary lesion of the peripheral part of the system, represented by a descending spinal projection, facilitates the recovery processes to develop during the subsequent destruction of its central part.

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Section: Discussionmentioning

confidence: 99%

Enhanced Behavioral Recovery from Sensorimotor Cortex Lesions After Pyramidotomy in Adult Rats

et al. 2000

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“…The thalamus is commonly referred to as the relay center of the brain because of its abundant connections with the cortex and involvement in multimodal sensory processing. Lesions of the thalamic nuclei have been associated with complex-movement deficits (Lee & Marsden, 1994), somatosensory challenges (Graff-Radford et al, 1985), and visuomotor impairments (Fabre & Buser, 1980). Yet, we know very little about how the thalamus develops in autism spectrum disorder (ASD), a disorder in which sensorimotor symptoms are commonly reported (Baranek et al, 2014; Fournier et al, 2010; Ming et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Longitudinal development of thalamic and internal capsule microstructure in autism spectrum disorder

et al. 2017

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Microstructure of the thalamus, a key sensory and motor brain area, appears to develop differently in individuals with autism spectrum disorder (ASD). Microstructure is important because it informs us of the density and organization of different brain tissues. During childhood, thalamic microstructure was distinct in the ASD group compared to the typically developing group. However, these group differences appeared to narrow with age, suggesting that the thalamus continues to dynamically change in ASD into adulthood.

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“…Despite its strategic position, and the promising motor-related reactivity of the VL nucleus, bilateral lesions have been found in cats and primates to have remarkably little effect on the execution of well-learned motor acts (Batuev, Cherenkova, & Yunatov, 1983; Bénita, Condé, Dormont, & Schmied, 1979; Fabre & Buser, 1979, 1980; Moll & Kuypers, 1975; Ranish & Soechting, 1976). The only deficits seen were limited to a very transient increase of reaction time.…”

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confidence: 99%

Visuomotor relearning after brain damage crucially depends on the integrity of the ventrolateral thalamic nucleus.

Fabre‐Thorpe¹,

Levesque²

1991

Behavioral Neuroscience

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The role of the ventrolateral thalamic nucleus (VL) has been analyzed in the phase of motor recovery that takes place when the execution of a previously learned movement has been perturbed by damage to another brain area. Cats were trained to perform a reaching movement toward a moving target-spot; they underwent bilateral brain lesions after performance had stabilized. A VL lesion induced a very transient increase of reaction time. The lesion of the main thalamic relay of the visual extrageniculate pathway (LP) severely disrupted accuracy and reaction time but was followed by full recovery. When both lesions were performed together, the deficits were similar to those induced by LP lesion alone, although they were more pronounced. However, the functional compensation was incomplete, and furthermore, the recovery of accuracy crucially depended on regular testing. These results support the involvement of VL in motor learning or relearning.

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Structures Involved in Acquisition and Performance of Visually Guided Movements in the Cat

Cited by 20 publications

References 48 publications

Enhanced Behavioral Recovery from Sensorimotor Cortex Lesions After Pyramidotomy in Adult Rats

Enhanced Behavioral Recovery from Sensorimotor Cortex Lesions After Pyramidotomy in Adult Rats

Longitudinal development of thalamic and internal capsule microstructure in autism spectrum disorder

Visuomotor relearning after brain damage crucially depends on the integrity of the ventrolateral thalamic nucleus.

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