In late 2019, the world was shaken when an unprecedented infectious pandemic, Coronavirus Disease, or Covid-19, broke out. As a result, all Malaysians are obligated to comply with and follow the new regulations based on guidelines provided by the Malaysian Ministry of Health (MOH). The situation affects the entire national education system regarding the Teaching and Learning (T&L) process. To ensure continuity in students' learning, the structure of T&L, which was previously conducted conventionally or face-to-face and centred on educators and students directly, has been changed to virtual and digital using the methods of Teaching and Learning at Home or Open and Distance Learning (ODL). Therefore, the purpose of this study is to find out the students in UiTM Melaka's perceptions on the effectiveness of teacher-made videos on YouTube as a teaching and learning tool during ODL. A set of questionnaires was distributed to students to seek input for this quantitative study. The data was analysed, and findings suggest that most of the students are highly interested in using lecturer-made videos in learning. In addition, students found that the use of YouTube assists them effectively in completing their course assignments and study assessments. As a result, it can be deduced that the use of lecturer-made videos in YouTube encourage the students to have meaningful learning experience and serve the aims of Open and Distance Learning.