Studies of the electrochemical behavior of epinephrine at a homocysteine self-assembled electrode

Zhang, Huimin; Zhou, Xin; Hui, Rutai; Li, Nanqiang; Liu, De-Pei

doi:10.1016/s0039-9140(01)00642-7

Cited by 81 publications

(29 citation statements)

References 20 publications

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“…The modified gold electrodes enhance the sensitivity towards epinephrine detection since at the bare gold the linearity between the current density and the epinephrine concentration was obtained in a narrower concentration range (1 mM to 500 mM) with the detection limit of 0.13 mM [30]. First and foremost, the range of concentrations over which the epinephrine content can be reliably estimated on the basis of the regression equation is broader than those reported in literature [6,7,13,20]. Moreover, the epinephrine detection limit achieved in this study with the use of the modified electrodes is lower to that obtained in [6,7,13].…”

mentioning

confidence: 88%

“…First and foremost, the range of concentrations over which the epinephrine content can be reliably estimated on the basis of the regression equation is broader than those reported in literature [6,7,13,20]. Moreover, the epinephrine detection limit achieved in this study with the use of the modified electrodes is lower to that obtained in [6,7,13]. It is worth pointing out that the c L obtained for the electrodes modified with TDPA are a little higher as compared with those obtained when macropropionic acid was used as modifying agent of the gold surface [30].…”

mentioning

confidence: 93%

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Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Łuczak

2009

Electroanalysis

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Thiodipropionoc acid (TDPA), cysteamine (CA) and gold nanoparticles (Au-NPs) modified gold pure electrodes have been applied in voltammetric sensors for simultaneous detection of epinephrine (EP), ascorbic (AA) and uric (UA) acids. Modified electrodes with self assembled layers (SAMs) show high selectivity, sensitivity, reproducibility and stability. A linear relationship between the epinephrine concentration and the current response is obtained in the range of 0.1 mM to 0.65 mM with the detection limit 0.065 mM for the electrodes modified at 2D surface and in the range of 0.1 mM to 0.75 mM with the detection limit 0.082 mM for the electrodes modified at the 3D surface.

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mentioning

confidence: 88%

mentioning

confidence: 93%

Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Łuczak

2009

Electroanalysis

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“…Among the different methods, electrochemical method has the advantage of simplicity, high sensitivity and selectivity. Electrodes modified with singlewalled carbon nanotubes [27], overoxidized dopamine [28], caffeic acid [29], SAMs of 3-mercaptopropionic acid [30], L-cysteine [31], homocysteine [32] and triazole [33] and gold nanoparticles [34,35] were used for the determination of EP. Although numerous electrochemical sensors for EP have been published in the literature fabrication of economically viable electrochemical sensor with higher selectivity, stability and sensitivity is still one of the challenging tasks for the electrochemists.…”

Section: Introductionmentioning

confidence: 99%

Selective Electrochemical Epinephrine Sensor Using Self‐Assembled Monomolecular Film of 1,8,15,22‐Tetraaminophthalocyanatonickel(II) on Gold Electrode

Sivanesan

John

2008

Electroanalysis

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This article describes the highly sensitive and selective determination of epinephrine (EP) using self-assembled monomolecular film (SAMF) of 1,8,15,22-tetraamino-phthalocyanatonickel(II) (4a-Ni II TAPc) on Au electrode. The 4a-Ni II TAPc SAMF modified electrode was prepared by spontaneous adsorption of 4a-Ni II TAPc from dimethylformamide solution. The modified electrode oxidizes EP at less over potential with enhanced current response in contrast to the bare Au electrode. The standard heterogeneous rate constant (k8) for the oxidation of EP at 4a-Ni II TAPc SAMF modified electrode was found to be 1.94 Â 10 À2 cm s À1 which was much higher than that at the bare Au electrode. Further, it was found that 4a-Ni II TAPc SAMF modified electrode separates the voltammetric signals of ascorbic acid (AA) and EP with a peak separation of 250 mV. Using amperometric method the lowest detection limit of 50 nM of EP was achieved at SAMF modified electrode. Simultaneous amperometric determination of AA and EP was also achieved at the SAMF modified electrode. Common physiological interferents such as uric acid, glucose, urea and NaCl do not interfere within the potential window of EP oxidation. The present 4a-Ni II TAPc SAMF modified electrode was also successfully applied to determine the concentration of EP in commercially available injection.

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“…The self-assembled monolayer approach is a good way to control the surface of electrodes at the molecular level [10,11]. It has grown enormously in recent years, primarily due to the easiness of fabrication, characterization, and manipulation.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Behavior of Dopamine at a Penicillamine Self‐Assembled Gold Electrode and its Analytical Application

Niu¹,

Luo²,

Li³

2006

Archiv der Pharmazie

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The fabrication and electrochemical characteristics of penicillamine (PCA) self-assembled monolayer modified gold electrode were investigated. The self-assembled electrode shows an obvious electrocatalytic activity for the oxidation of dopamine (DA). In phosphate buffer (pH 7.0), the peak current is proportional to the concentration of DA in the range of 8.0 x 10(-6) approximately 1.0 x 10(-3) M by the cyclic voltammetry methods with the detection limits of 4.5 x 10(-7) M. The PCA self-assembled monolayer modified gold electrode can be applied to the determination of DA in practical injection samples with simplicity, rapidness, and accurate results.

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Studies of the electrochemical behavior of epinephrine at a homocysteine self-assembled electrode

Cited by 81 publications

References 20 publications

Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Epinephrine Oxidation in the Presence of Interfering Molecules on Gold and Gold Electrodes modified with Gold Nanoparticles and Thiodipropionic Acid in Aqueous Solution. A Comparative Study

Selective Electrochemical Epinephrine Sensor Using Self‐Assembled Monomolecular Film of 1,8,15,22‐Tetraaminophthalocyanatonickel(II) on Gold Electrode

Electrochemical Behavior of Dopamine at a Penicillamine Self‐Assembled Gold Electrode and its Analytical Application

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