Studies on chemical fingerprints of Siraitia grosvenorii fruits (Luo Han Guo) by HPLC

Abstract

A novel, efficient, and accurate fingerprinting method using high performance liquid chromatography-photodiode array detection has been developed and optimized for the investigation and demonstration of the variance in chemical properties among Siraitia grosvenorii fruits from different origins. The effects of growth stages, cultivated varieties, collection locations, and fruit portions of the herb on chromatographic fingerprints were examined. Eleven compounds were identified on chromatograms by comparing the retention time and UV spectrum of each peak separately with those of external references. The results revealed that chromatographic fingerprints, combining similarity or hierarchical clustering analysis along with reference compounds, could efficiently identify and distinguish S. grosvenorii fruits from different sources, which provided helpful clues for studying the plants' secondary metabolites and benefitted quality control.

Liquid chromatography with tandem mass spectrometry method for the simultaneous determination of multiple sweet mogrosides in the fruits ofSiraitia grosvenoriiand its marketed sweeteners

“…According to the report, unripe fruits mainly contain mogrosides of IIE and III, while ripe fruits have higher MV. The MV content significantly increased, while the levels of mogroside IIE and III dramatically decreased with increased growing time (disappeared after 70 DAA) [26,39].…”

Quality evaluation of the leaves of Magnolia officinalis var. biloba using high‐performance liquid chromatography fingerprint analysis of phenolic compounds

“…HCA is a multivariate analysis technique that has been applied while performing fingerprint analysis; it is used to sort out the samples into groups. Herbs can be classified by HCA according to the peak areas of their corresponding LC fingerprints . HCA has been used to evaluate the qualities of different herbs .…”

“…Herbs can be classified by HCA according to the peak areas of their corresponding LC fingerprints [31]. HCA has been used to evaluate the qualities of different herbs [10].…”

Quality Evaluation of Corydalis yanhusuo by High-Performance Liquid Chromatography Fingerprinting Coupled with Multicomponent Quantitative Analysis

“…Therefore, we also need to combine pharmacodynamic research and the correlation analysis of the material basis of secondary metabolites, we can tell which sample was be 'reference' of good quality. 29 , has been widely applied to fingerprint analysis, as it permits simple nonparametric data interpretation 30 and provides a visual representation of complex data. Herein, a method known as average linkage between groups was applied, and Pearson correlation was selected as a measurement.…”