Studies on the anti-inflammatory and analgesic activity of Cedrus deodara (Roxb.) Loud. wood oil

Shinde, Ujwala A.; Phadke, A.S; Nair, Anupama; Mungantiwar, Ashish; Dikshit, V.J; Saraf, M. N.

doi:10.1016/s0378-8741(98)00150-0

Cited by 100 publications

(44 citation statements)

References 6 publications

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“…Eddy's hot plate 15 The temperature of hot plate was set at 55±1°C, with the help of thermostat. Animals were placed on the hot plate with the paws touching the plate.…”

Section: Evaluation Of Analgesic Activitymentioning

confidence: 99%

Anti-inflammatory and analgesic properties of Ocimum sanctum: a comparative study using animal models

Umamageswari

Kudagi

2015

Int J Basic Clin Pharmacol

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“…Eddy's hot plate 15 The temperature of hot plate was set at 55±1°C, with the help of thermostat. Animals were placed on the hot plate with the paws touching the plate.…”

Section: Evaluation Of Analgesic Activitymentioning

confidence: 99%

Anti-inflammatory and analgesic properties of Ocimum sanctum: a comparative study using animal models

Umamageswari

Kudagi

2015

Int J Basic Clin Pharmacol

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“…In ayurvedic text, Yashtimadhu is described as Chakshushya Dravya 6 . The wood of C.deodara also has potent anti-inflammatory & analgesic activity 8 . Nelumbo nucifera has antioxidant activity may be due to the presence of phenolics, alkaloids, and saponins 9 .…”

Section: Resultsmentioning

confidence: 99%

A Clinical Study on the Role of Tarpana Kriya Kalpa With Shatavahadi Ghrita in the Management of Shushkakshi-Paka With Special Reference to Dry Eye Syndrome

Tripathi¹,

Sharma²,

Sharma³

2017

Int. J. Res. Ayurveda Pharm.

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Shushkakshi-paka(Dry Eye Syndrome) a common ophthalmic condition. Due to its variegated etiology, multifactorial pathophysiology, lack of gold standard diagnostic procedure and absence of any curative modality, it presents as a great challenge to physician's skills. In this clinical trial, local therapy Tarpana Kriya Kalpa with Shatavahadi Ghrita has been selected for the clinical management of Dry Eye Syndrome. An open random comparative study was planned on 40 patients with clinical features of Shushkakshipaka and divided randomly into two therapeutic groups of 20 patients each. In group A, Tarpana with Shatavahadi Ghrita and in Group B, Tarpana with Goghrita was done for 7 days. In comparative study over criteria of assessment, no statistically significant difference was observed between two therapies except in symptom Foreign Body Sensation. Though Group A faired far well on the basis of percentage relief.

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“…The herbal constituents of emulsion i.e. Melaleuca alternifolia oil, Rosmarinus officinalis oil, Mentha arvensis oil along with Citrus limon are reported to possess antibacterial, antimicrobial, anti-inflammatory and antiseptic potential 15,16,17 . So the formulation in present study was found to be non corrosive/irritant.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Diagnostic Parameters to Detect Induction of Acne, Acute Dermal Irritation and Corrosion Potential of a Polyherbal Formulation

Kumar¹,

Berwal²,

Kumar³

et al. 2017

Int. J. Res. Ayurveda Pharm.

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The current protocol was designed to evaluate and detect the new parameters of acne induction (Histological lesion), Acute Dermal Irritation and corrosion potential of a polyherbal nano emulsion (obtained from research and development of Venus Medicine Research Centre, Baddi, H.P, India) according to Organisation for Economic Co-operation and Development (OECD) guidelines. Materials and Methods: Polyherbal drug, a new micro emulsion for topical use applied on the dorsal area of the trunk, has been developed as an anti-acne herbal nano-emulsion. Polyherbal drug's active ingredients include herbal extracts of Melaleuca alternifolia oil, Rosmarinus officinalis oil, Mentha arvensis oil along with Citrus limon are tested for their antibacterial, antimicrobial, anti-inflammatory and antiseptic effects. Serialise testing approach is recommended for developing scientifically sound data on the corrosivity/irritation of a new substance. Young healthy albino rabbits were used for the initial corrosivity/irritation study. If corrosive response was not found in the initial test, the irritant or negative response was confirmed using three additional animals each with one patch for an exposure period of four hours. Each animal served as its own control. After application of polyherbal emulsion the degree of irritation/corrosion and histological lesions were read and scored. Results: No severe erythema, oedema or any histological lesions were observed after polyherbal nanoemulsion application. The results revealed no irritation potential of polyherbal nanoemulsion. Conclusion: polyherbal nanoemulsion is safe formulation for topical use.

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Studies on the anti-inflammatory and analgesic activity of Cedrus deodara (Roxb.) Loud. wood oil

Cited by 100 publications

References 6 publications

Anti-inflammatory and analgesic properties of Ocimum sanctum: a comparative study using animal models

Anti-inflammatory and analgesic properties of Ocimum sanctum: a comparative study using animal models

A Clinical Study on the Role of Tarpana Kriya Kalpa With Shatavahadi Ghrita in the Management of Shushkakshi-Paka With Special Reference to Dry Eye Syndrome

Evaluation of Diagnostic Parameters to Detect Induction of Acne, Acute Dermal Irritation and Corrosion Potential of a Polyherbal Formulation

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