Study and characterization of tobacco mosaic virus head-to-tail assembly assisted by aniline polymerization

A supramolecular strategy to assemble multifunctional viral nanoparticles

“…3,4 Recently, inspired by the hierarchical structures of biogenic viral particles, multifunctional virus-like nanostructures have been constructed from synthetic polymers. 5,6 In the meantime, the application of viral nanoparticles (VNPs) derived from plants and bacteria in biomedical fields has also attracted great attention, primarily due to their well-defined, programmable, multivalent and monodispersed structural features [7][8][9][10][11][12][13][14][15][16][17][18][19] as well as their good biocompatibility. 20,21 To make the best use of the inherent compositions and structures of VNPs, many multifunctional VNPs have been constructed by the combination of mutagenesis and bioconjugation approaches, by which a variety of targeting ligands, catalytic units, diagnostic probes and therapeutic cargos have been anchored on the surface or inside of the internal cavity of VNPs.…”

“…20,21 To make the best use of the inherent compositions and structures of VNPs, many multifunctional VNPs have been constructed by the combination of mutagenesis and bioconjugation approaches, by which a variety of targeting ligands, catalytic units, diagnostic probes and therapeutic cargos have been anchored on the surface or inside of the internal cavity of VNPs. 12,[22][23][24][25][26][27][28][29] On the other hand, supramolecular interactions have been extensively applied to constructing drug and gene delivery systems, as well as smart materials due to their modularity, reversibility and stimuli-responsiveness. [30][31][32][33][34][35][36] For example, b-cyclodextrin (b-CD), a natural toroid-shaped cyclic oligosaccharide, is one of the most widely used host-systems in supramolecular chemistry thanks to its low cost, good water solubility and biocompatible properties.…”

Bacteriophage M13 as a scaffold for preparing conductive polymeric composite fibers

“…Previously we have shown that by using TMV as the template, 1-D polyaniline/TMV composite nanowires can be prepared by a head-to-tail selfassembly process of TMV [13,14]. Polyaniline (PANi) is a conducting polymer that has been extensively studied for optical and electronic applications [24 28].…”

“…The controlled growth and fabrication of onedimensional (1-D) nanostructured objects such as fibers, tubes, and rods, is an emerging research area due to their potential applications in developing nanosized electric devices, sensors, catalysts, and energy storage units Previously we have shown that by using TMV as the template, 1-D polyaniline/TMV composite nanowires can be prepared by a head-to-tail selfassembly process of TMV [13,14] M13 is a cylindrical protein capsid consisting of 2700 identical major coat proteins as well as several minor coat proteins surrounding a single-stranded DNA genome. The rod-like M13 is 880 nm in length and 6.6 nm in diameter and one of the most studied rod-like viruses for developing new biocomposite materials [35].…”

Tobacco mosaic virus based thin film sensor for detection of volatile organic compounds

“…22 TMV has been employed as a building block or template to produce materials with applications in light harvesting, electronics, energy storage, and cell culturing. 3,[23][24][25][26][27] On the other hand, conducting polymers have found broad applications in electronics, imaging and sensing. [28][29][30] In particular, polyaniline (PANI) has received considerable attention due to its environmental stability, ease of synthesis and its well known physical properties.…”