Study of Lime Peel Flavonoid as effectively Antibacterial against Methicillin-Resistant Staphylococcus aureus

Ekawati, Evy Ratnasari; Windarmanto, Windarmanto; Wahyuningsih, Sri Puji Astuti

doi:10.52711/0974-360x.2022.00501

Cited by 5 publications

(1 citation statement)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The zone of inhibition can be measured manually using a ruler. The inhibition zone is calculated by subtracting the diameter of the inhibition zone from the diameter of the paper disc, but after that the units obtained must be changed to millimeters (mm) [30,31]. The results of the inhibitory zone of U. lactuca crude extract against the growth of P. acnes and S. aureus bacteria are shown in the Table 5.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial activity of crude extracts Ulva lactuca against Staphyloccocus aureus and Propionibacterium acne

Aprillia,

Adam,

Supii

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

Sources of antibiotic raw materials as a reliever / acne remover drug is needed. Especially of natural ingredients from the Ulva lactuca. This study aims to examine the potential of crude extracts of U. lactuca as an antibacterial against Staphyloccocus aureus and Propionibacterium acne. Extraction of U. lactuca used Microwave Assited Extraction (MAE) technique with different types of solvents and extraction time. Analysis of antibacterial activity was carried out by the paper disk diffusion method. The research design used was a Factorial Completely Randomized Design (CRD) with two factors. The first factor of type solvent;ethanol, ethyl acetate and aquades. The second factor of extraction time which consists of 3 different levels;10 minutes, 20 minutes, and 30 minutes. The results of the study The highest yield was obtained in ethanol by 30 minutes extraction time;average of 24.9%. Phytochemical compounds were detected used a color test on the extract of Ulva lactuca namely alkaloids, steroids, flavonoids, and tannins. Whereas the antibacterial test with the highest tasteless zone of Staphylococcus aureus bacteria with ethanol solvent extraction time of 30 minutes;average of 17.17 mm. Crude extract of U. lactuca has potential as an antibacterial S. aureus and P. acne.

show abstract

Section: Resultsmentioning

confidence: 99%

Antibacterial activity of crude extracts Ulva lactuca against Staphyloccocus aureus and Propionibacterium acne

Aprillia,

Adam,

Supii

et al. 2023

IOP Conf. Ser.: Earth Environ. Sci.

View full text Add to dashboard Cite

show abstract

Ethnopharmacological potential of an Unexplored tropical shrub, Glochidionlittorale Blume

Hassan

Ibrahim

Mohammed

et al. 2023

RJPT

View full text Add to dashboard Cite

The phytochemical contents of the Glochidionlittorale Blume has not been studied enough as compared to other related medicinal plants, but traditional usage of this tropical shrub suggests the presence of beneficial pharmacological properties. To assess the presence of common phytochemical constituents as well as to determine the total phenolic and total flavonoid contents in G. littorale fruit extracts. Two different solvents (ethanol and ethyl acetate), phytochemicals from G. littorale fruits were extracted and used to assess their antioxidative and free radical scavenging properties. Ethanolic extract possesses higher amount of TPC and TFC as compared to ethyl acetate extract. To our knowledge, this is the first systematic study on screening bioactive compounds in G. littorale fruits. This tropical shrub might be a good source of natural antioxidants and beneficial phytochemicals.

show abstract

The Effect in Vivo and in Silico Citronella Grass Extract (Cymbopogon nardus L.) on the Plasma ACE Inhibitory activity and Antihypertensive effect

Solekha,

Tri Puspaningsih,

Ika Setiyowati

et al. 2023

RJPT

View full text Add to dashboard Cite

The mechanism of hypertension is through the formation of angiotensin I into angiotensin II by Angiotensin I Converting Enzyme (ACE) which causes constriction of blood vessels resulting in narrowing of blood vessels. A number of extracts and compounds derived from plants have been proven in vitro as ACE inhibitors including flavonoids. This compound produces the ability to reduce oxidative stress, inhibit angiotensin converting enzyme (ACE) activity, promote vascular endothelial relaxation, and regulate cell signaling and gene expression by lowering Heat Shock Protein 70(HSP 70). The purpose of this study was to determine the effectiveness of the optimal dose of Cymbopogon nardus (L.) Citronella grass extract in its activity as a hypertension reducer and the effectiveness of the compound for inhibiting HSP-70 as an antihypertensive. The study employed bioinformatics modeling in its effectiveness in inhibiting HSP-70 in silica and in vitro using Cymbopogon nardus (L.) Citronella grass extract with various doses of 25, 50, and 100mg/kg BW in BALB/C mice. Na-CMC was used as a positive control and lead acetate was used as a negative control. Modeling with in silico method was used to observe the inhibition of compounds from Citronella grass stems against heat shock protein 70(HSP-70). The in vitro method with the maceration method was used in its extraction. The HPLC method was used for testing ACE inhibitors. The results of this study were treated with Na-CMC suspension (66.3±1.2%), acetic acid (65.7±0.7%), a dose of 25mg/kg BW (80.9±1.3%), a dose of 50 mg/kg BW was 88.2±1.7 and a dose of 100mg/kg BW (93.9±2.5%). In conclusion, HSP-70 can be used as an indicator of in silico inhibition of hypertension and is effective in reducing hypertension in vitro.

show abstract

Study of Lime Peel Flavonoid as effectively Antibacterial against Methicillin-Resistant Staphylococcus aureus

Cited by 5 publications

References 25 publications

Antibacterial activity of crude extracts Ulva lactuca against Staphyloccocus aureus and Propionibacterium acne

Antibacterial activity of crude extracts Ulva lactuca against Staphyloccocus aureus and Propionibacterium acne

Ethnopharmacological potential of an Unexplored tropical shrub, Glochidionlittorale Blume

The Effect in Vivo and in Silico Citronella Grass Extract (Cymbopogon nardus L.) on the Plasma ACE Inhibitory activity and Antihypertensive effect

Contact Info

Product

Resources

About