Study of metastasis in lymph node by fine needle aspiration cytology: our institutional experience

Patel, Mandakini M.; Italiya, Sonal L.; Dhandha, Zarana B.; Dudhat, Reena B; Kaptan, Kumarbhargav; Shah, Mitesh; Mansuri, Benazeer M.; Thumar, Kazumi V.; Makwana, Gopal R.

doi:10.5455/2320-6012.ijrms20131128

Cited by 11 publications

(11 citation statements)

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“…of cases was metastatic squamous cell carcinoma, followed by duct carcinoma breast in present study. Our findings correlated with other studies of Wilkinson et al, Pandav AB et al and mandakini et al 7,9,10 The incidence of metastasis was more in males (73.1%) as compared to females (26.8%), with male to female ratio 2.6:1. Male preponderance was noted in our study, which correlates with other studies of Khajuria et al and Pandav AB et al 8,9 This may be because of decreased incidence of various addictions in females.…”

Section: Discussionsupporting

confidence: 82%

“…of cases was found in cervical region and metastatic squamous cell carcinoma was the most frequent subtype. Similar findings were observed by Khajuria et al Wilkinson et al and Mandakini et al 7,8,10 In present study, out of 97 cases of metastatic tumors, maximum no. of cases was metastatic squamous cell carcinoma, followed by duct carcinoma breast in present study.…”

Section: Discussionsupporting

confidence: 80%

“…The most common age group affected in metastatic tumour, in present study was 51-60 years which correlate with other study of Khajuria et al and Pandav AB et al However, Mandakini et al found maximum cases in age group 41-50 years. [7][8][9] The metastatic lymph nodes were located in anterior and posterior cervical triangles, supraclavicular area, axilla, abdomen and inguinal region, the most common site was Cervical lymph nodes comprising 73 cases. In present study, maximum no.…”

Section: Discussionmentioning

confidence: 99%

“…4 FNAC is a reliable diagnostic tool for lymphadenopathy in adult patients who are suspected for malignancy as it has less complication, is a simple procedure and can be repeated easily. 7 This procedure is cost effective and well tolerated by the patients and can be performed on outpatient basis. 3 Aim of this study was to determine the frequency of different metastatic lesions of lymph nodes.…”

Section: Introductionmentioning

confidence: 99%

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A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

Meena

Mishra

2017

Int J Res Med Sci

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Background: FNAC is rapidly emerging as a useful tool in the diagnosis of metastatic lesion of lymph nodes. FNAC not only confirms or excludes metastasis in a case of a known primary malignancy but, also, in most cases helps to detect occult primary malignancy. Aim of present study was to determine the frequency of metastatic lesions of lymph nodes.Methods: This retrospective study was done of all metastatic lymph node lesions reported on FNAC, in the department of pathology, NSCB medical college, Jabalpur from January 2014 to December 2014 (One Year).Results: Total cases of 400 lymph node aspiration were done, of which 120 cases were clinically suspicious of metastasis. Cytology results were positive for metastasis in 97 cases (80.8%). The most common site of aspiration was cervical lymph nodes (75.2%). Maximum number of cases of metastasis were in 51-60 years age group with male predominance (male:female 2.6:1). The most common metastasis was squamous cell carcinoma seen in 74 cases (76.2%), followed by metastatic mammary carcinoma (10.3%), remaining were adenocarcinoma, undifferentiated carcinoma, malignant melanoma, papillary thyroid carcinoma and transitional cell carcinoma.Conclusions: FNAC is a rapid, safe and cost-effective technique. It gives early and accurate results with minimal invasion and reduces the need for surgical biopsies, thus saves cost and time to reach the final diagnosis. It is therefore concluded that FNAC is a useful tool in diagnosing metastatic lesions of lymph nodes with a good certainty.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

Meena

Mishra

2017

Int J Res Med Sci

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“…Lymph node aspirates in 28 cases (10.4%) showed metastatic deposits. This is in correlation with the studies by Patel et al, Ghartimagar et al and Bhavani et al where metastatic deposits were seen in 27.06%, 18% cases and 9.5% respectively [27,28,29]. Most of the metastatic deposits were from squamous cell carcinoma arising commonly in the tongue, alveolus, buccal mucosa, palate and from lung followed by adenocarcinoma.…”

Section: Original Research Articlesupporting

confidence: 91%

Study of fine needle aspiration cytology of lymphadenopathy in tertiary care centre of Ahmedabad, Gujarat

Sharma¹,

Dharaiya

2018

Trop J Pathol Microbiol

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Introduction: Lymph nodes are a site for organized collections of lympho-reticular tissue and are pink gray bean shaped encapsulated organs. Lymphadenopathy is one of the most common clinical presentations of patients attending the outpatient department. Lymph nodes are among the commonly aspirated organs for diagnostic purposes. Fine-needle aspiration cytology (FNAC) is a clinical technique used to obtain cells, tissues and/or fluid through a thin needle attached with disposable syringe for the purpose of diagnosis of masses. Aims and Objectives: The aims of this study is to find out the frequency of lymphadenopathy, etiological factors and cyto-morphologial features in different age groups and incidence of various lymph node diseases on fine-needle aspiration cytology (FNAC) and to analyze the utility and diagnostic importance of FNAC in lymph node diseases. Materials and Methods: The present study was carried out in Department of Pathology at GMERS Medical College, Sola-Ahmedabad, Gujarat a Tertiary Care Centre. A total of 268 patients of all age groups underwent FNAC of enlarged lymph nodes during this study period. Results: Tuberculous lymphadenitis was recorded as the most common presentation of lymphadenopathy in the cervical region. Male to female ratio is 1:1.13. Most common causes of lymphadenopathy in 11-40 years age group was tubercular lymphadenitis and metastatic carcinoma in patients >50 years of age. Conclusion: FNAC of lymph nodes is an excellent first line investigation to determine the nature of lesion. It is quick, safe, minimally invasive, and reliable and is readily accepted by the patient.

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Limitations in Cytodiagnosis- An Institutional Study

Uma¹,

Rajani²

2018

jemds

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BACKGROUND Fine needle aspiration cytology has replaced open biopsy in majority of the palpable lesions. Differentiation between benign and malignant lesions is possible with this procedure with low cost, but has certain limitations. In the present study, the limitations of cytodiagnosis in various palpable lesions in the body is analysed.The aim of the study was to know the prevalence of various lesions which could be diagnosed on cytology, its limitations and need for histopathological examination. MATERIALS AND METHODSA prospective observational study was conducted in the Department of Pathology at tertiary care centre in rural area. 1200 cases attending for fine needle aspiration for a period of 2 years from January 2014 to December 2015 was taken up for the study. After obtaining informed consent from the patients, fine needle aspiration was performed using a 22 -24 gauge needle with 10 mL syringe and long lumbar puncture needle for guided aspirations. Smears were fixed in 95% isopropyl alcohol and stained with Haematoxylin and Eosin. Air dried smears were stained with May-Grunwald stain and special stains were done wherever necessary. The tissue was subjected for histopathological examination wherever indicated and results tabulated. Overall diagnostic accuracy, sensitivity and specificity of cytology as a diagnostic procedure was calculated. RESULTSThe overall accuracy of diagnosing granulomatous lymphadenitis and lymphoproliferative disorders on cytology was 65.71%. The overall accuracy of diagnosing fibrocystic disease of breast proliferative type was 80% and ductal carcinoma of breast was 100% on cytology. The overall accuracy of diagnosing follicular adenoma of thyroid was 36.20% and malignancy was 100% on cytology. The overall accuracy of diagnosing both benign and malignant lesions of salivary gland was 100% on cytology. The overall accuracy of diagnosing soft tissue tumours was 88.67% on cytology. In lesions of bone, skin and ultrasonographic-guided lesions of abdomen, the overall accuracy was 100%. On Pap smears, the overall accuracy was 84.48%. CONCLUSIONIn cases of granulomatous lymphadenitis without significant necrosis and negative AFB, fibrocystic disease of breast, follicular adenoma of thyroid, vascular tumours, soft tissue tumours with nuclear atypia and cases of atypical squamous cell of undetermined significance and high-grade intraepithelial lesions on Pap smears need histopathological examination for accurate diagnosis.

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Study of metastasis in lymph node by fine needle aspiration cytology: our institutional experience

Cited by 11 publications

References 4 publications

A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

A study of metastatic lesions of lymph nodes by fine needle aspiration cytology

Study of fine needle aspiration cytology of lymphadenopathy in tertiary care centre of Ahmedabad, Gujarat

Limitations in Cytodiagnosis- An Institutional Study

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