Study of serum electrolytes in acute exacerbation of chronic obstructive pulmonary disease patients

Goli, Gnaneshwar; Mukka, Rajender; Sairi, Sunil

doi:10.18203/2320-6012.ijrms20162287

Cited by 4 publications

(7 citation statements)

References 12 publications

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“…Study by Das P et al 10 shows a significantly low level of mean serum sodium (133±6.86 mmol/L) in subjects with acute exacerbation of COPD. Another study in India by Goli G et al 11 shows mean serum sodium 132±5.65mmol/L. In our study, mean serum sodium level was 133.82±2.52 mmol/L.…”

Section: Resultsupporting

confidence: 57%

“…Das P et al 10 in their study found a low level of potassium (3.39 ± 0.96 mmol/L)) in subjects with acute exacerbation of COPD. Another study by Goli G et al 11 in India shows mean serum potassium level of 3.29±0.96 mmol/L). Due to serum potassium maintains a narrow range, the minimum variation of level is important for clinical assessment and management of patient.…”

Section: Resultmentioning

confidence: 87%

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Pattern of Serum Electrolytes Imbalance among Patients with Acute Exacerbation of COPD Admitted in a Tertiary Level Hospital

Saha

Ali²,

Islm

et al. 2020

Faridpur Med Coll J

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Chronic Obstructive Pulmonary Disease (COPD) is a progressive disease and there is not yet a cure. Not only in Bangladesh but also worldwide the incidence of COPD is increasing. The disease is associated with some metabolic derangement such as electrolytes imbalance. Those factors further worsen the disease course. As a result COPD related morbidity, mortality and cost to health systems are also increasing. This cross-sectional observational study was conducted in Faridpur Medical College Hospital (FMCH) over 6 months among 100 patients who were admitted with acute exacerbation of COPD. The mean age was (58.13 ± 9.96) years. In this study serum electrolytes were found below the normal range in 68 (68%) cases and within normal range in 32(32%) cases. Isolated hyponatremia was observed in 36(53%) and 15(22%) had isolated hypokalaemia. Both hyponatremia and hypokalaemia was found in 17(25%) cases. The mean serum sodium level was (133.82±2.52) mmol/l. Among patients with isolated hyponatremia, 24(67%) had mild hyponatremia and 12(33%) got moderate hyponatremia. Again the mean serum potassium was (3.45±0.23) mmol/l. Among patients with isolated hypokalaemia, 10(67%) had mild hypokalaemia and 5(33%) had moderate hypokalaemia. Both hyponatremia and hypokalaemia was observed in one fourth of total electrolytes depleted cases and all were within the mild range. No patient had severe hyponatremia or hypokalaemia. Faridpur Med. Coll. J. Jan 2020;15(1): 24-27

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Section: Resultsupporting

confidence: 57%

Section: Resultmentioning

confidence: 87%

Pattern of Serum Electrolytes Imbalance among Patients with Acute Exacerbation of COPD Admitted in a Tertiary Level Hospital

Saha

Ali²,

Islm

et al. 2020

Faridpur Med Coll J

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“…34 Some authors have described hyponatremia in COPD exacerbation. 35,36 Although the mechanism by which hyponatremia occurs in COPD has not been fully elucidated, it has been suggested that hypercapnia decreases renal blood flow, thereby increasing the retention of water and sodium and causing edema and hyponatremia. 37 Our study found a significant correlation between hyponatremia and lung disease.…”

Section: Discussionmentioning

confidence: 99%

Hyponatremia in elderly patients with fragility fractures of the proximal femur: a cross-sectional study

2019

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Introduction: Proximal femur fractures affect the mortality and morbidity of elderly individuals. Recent studies have shown an association between fragility fractures and hyponatremia, a common fluid and electrolyte balance disorder. Objectives: This study aimed to investigate the occurrence of hyponatremia in patients with fragility fractures of the proximal femur. Methods: The authors looked into the data from the medical records of patients admitted to the emergency unit of the Real Hospital Português for fragility fractures of the proximal femur from 2014 to 2017. The study included patients with serum sodium levels recorded in their charts. Results: Fourteen of 69 (20.3%) patients with proximal femur fractures had hyponatremia. The main factors linked to hyponatremia were lung disease, and prescription of amiodarone and/or antidepressants. Conclusion: In elderly individuals, fragility fractures of the proximal femur may correlate with hyponatremia, particularly among patients on amiodarone or antidepressants.

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“…5 Hyponatremia should be checked and corrected routinely in hospitalized patients to avoid fatal outcome. 4 Hyponatremia in COPD admitted patients was found about 15.4%. 4 In other study hyponatremia was found 20% in patients admitted with acute COPD exacerbation.…”

Section: Introductionmentioning

confidence: 97%

“…3 In COPD patients with hyponatremia had worse clinical outcome than COPD patients with normal serum sodium level. 4 Hyponatremia in COPD can result from increased salt and water retention due to heart failure, effect of treatment drugs and syndrome of inappropriate antidiuretic hormone release. 5 Hyponatremia should be checked and corrected routinely in hospitalized patients to avoid fatal outcome.…”

Section: Introductionmentioning

confidence: 99%

Frequency of Hyponatremia in Chronic Obstructive Pulmonary Disease Patients

Parvez¹,

Sajjad²,

Gul³

et al. 2022

PJMHS

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Aim: To determine the frequency of hyponatremia in chronic obstructive pulmonary disease patients. Study Design: Cross-sectional-study Place and duration of study: Medical "A" Unit, MTI Ayub Teaching Hospital Abbottabad from 23rd July 2019 to 22nd January 2020. Methodology: Two hundred and one patients presenting with chronic obstructive pulmonary disease (COPD) were enrolled. Results: One hundred and thirty five (67.2%) patients were male while 66 (32.8%) patients were females. In 30 (14.9%) patients have hyponatremia. Conclusion: Hyponatremia is prevalent in COPD patients, and its frequency was quite higher in patients admitted with COPD. Thus, hyponatremia patient’ should be monitored carefully. Keywords: Chronic obstructive pulmonary disease, Hyponatremia, Sodium levels

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Study of serum electrolytes in acute exacerbation of chronic obstructive pulmonary disease patients

Cited by 4 publications

References 12 publications

Pattern of Serum Electrolytes Imbalance among Patients with Acute Exacerbation of COPD Admitted in a Tertiary Level Hospital

Pattern of Serum Electrolytes Imbalance among Patients with Acute Exacerbation of COPD Admitted in a Tertiary Level Hospital

Hyponatremia in elderly patients with fragility fractures of the proximal femur: a cross-sectional study

Frequency of Hyponatremia in Chronic Obstructive Pulmonary Disease Patients

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