Study of Serum Vitamin D Level in Different Socio-Demographic Population - A Pilot Study

Hossain, Homayra Tahseen; Islam, Quazi Tarikul; Khandaker, Abul Kashem; Ahasan, Ham Nazmul

doi:10.3329/jom.v19i1.34836

Cited by 26 publications

(29 citation statements)

References 14 publications

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“…41 Another cross-sectional study to evaluate the association between Vitamin-D and hypertension among 520 people supports the study as the result stated that Severe vitamin D de ciency was highly prevalent in people with hypertension than in people without hypertension (p value <0.001). The study concluded that Vitamin D de ciency was associated with an increased risk of having hypertension .38 In our current study subjects 25% (27) had chronic illness history with hypertension and the Karl pearson correlation coe cient showed positive relation as well signi cant association with Serum Vitamin D level of Nepalese residents. A Similar Case-control study aimed to assess the serum level of vitamin D in cerebral stroke patients and secondly, to examine if its de ciency was associated with stroke severity and outcome result revealed that studied stroke patients had statistically signi cant lower levels of vitamin D. Multivariable analysis of the signi cant variables showed that old age (OR = 1.072), dyslipidemia (OR = 3.588), vitamin D de ciency (OR = 4.790), and large infarction size (OR = 7.462) was independently associated with stroke severity.…”

Section: Discussionsupporting

confidence: 47%

“…26 Again contradicted by another crosssectional study on serum vitamin D level in different 222 socio-demographic population The mean difference between normal and obese population was statistically signi cant (p= 0.007). 27 Present study revealed that serum vitamin-D level was signi cantly associated with gender (χ2=0.233, p=0.003), marital status (χ2=0.562, p=0.014), address (i.e. Terai, Hilly and mountain region) (χ2=4.431, p=0.009) and physical activity (χ2=0.193, 0.013).…”

Section: Discussionmentioning

confidence: 57%

See 1 more Smart Citation

Vitamin-D in Nepal: are we really vitamin-D deficient?

Chandra¹,

Pant²,

Rajbhandari³

et al. 2020

Preprint

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Background: Recently, there have been a surge in research worldwide regarding relation of vitamin D with several diseases. Many neurological diseases like multiple sclerosis, Alzheimer’s disease as well as other diseases like cardiovascular disease have shown positive correlation with vit. D deficiency measured according to the international level. Most of the research on possible role of vitamin D has been carried out in America and European nations, while there is paucity of research in low- and middle-income nations (LMICS) that are nearer to the equatorial area. In countries like Nepal, geographically they lie near to the equator and sunlight exposure is well enough and milk consumption is quite moderate. Thus, special consideration for vitamin D level in Asian population seems plausible. This will not only help us to cover the vitamin D deficient population but will help us to avoid excessive and unnecessary usage of it.Objectives: This study aims to detect the situation of vitamin D in Nepalese population and secondly to find out the suitable normalized reference range for serum vitamin D in multi-ethnic Nepalese population.Methodology: This was a hospital based prospective study. A prospective study was conducted using purposive sampling technique with in-vivo and in vitro bio-physiological method to collect serum vitamin D level. After rigorous inclusive and exclusive criteria, a total of 107 subjects were collected.Result: The present study showed that 32% of participants had deficit serum Vitamin-D level (<15 ng/mL), 48% of subjects had insufficient serum level of Vitamin-D (15-<30ng/mL) and 20% of participants had sufficient serum level of Vitamin-D (>30ng/mL). Study showed that there is lower degree of positive relationship of Body Mass Index (BMI) with Serum Vitamin-D level (r=0.162, p=0.094), History of chronic illness (χ2=0.10, p=0.03), timing of occurrence of stroke (χ2=11.41,p=0.017) and diagnosis (χ2=21.19, p=0.011) had significant association with Serum vitamin-D level at p<0.05.Conclusion: There is direct significant association of Serum Vitamin D with socio-demographic variables when international unit is considered. Neurological disorder showed positive association with serum vitamin D level.

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Section: Discussionsupporting

confidence: 47%

Section: Discussionmentioning

confidence: 57%

Vitamin-D in Nepal: are we really vitamin-D deficient?

Chandra¹,

Pant²,

Rajbhandari³

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…Different picture was found in a Bangladeshi study done by Hossain HT et al; Highest percentage (37.5%) of severely deficient vitamin D level (<10 ng/ml) was found in 31-50 years of age. 10 In our study among female vitamin D sufficient level was highest (39.2%) in younger age group 11 -20 years next sufficient level (30.8%) was in 21 -30 years. At these ages persons are active remain outside and exposed to sun more.…”

Section: Discussionsupporting

confidence: 41%

A study on vitamin D level among the patients attending in a private chamber in Dhaka city

Eva¹,

Begum²,

Kabir³

et al. 2020

Northern Int. Med. Coll. J.

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Background : Vitamin D deficiency is one of the most neglected public health issues all over the world. Near about 1 billion people round the world suffer from vitamin D deficiency. Most of the countries in Asia having high prevalence of vitamin D deficiency.Objective : To find the vitamin D level among the patients attending in a private chamber in Dhaka city Methodology : A cross sectional observation study was carried out in a renowned diagnostic center of Dhaka city from July 2017 to June 2018. A sample of 1523 adult patients aged 18 years and above, presented with generalized body aches and pains selected conveniently for the study. Blood samples were taken and serum vitamin D levels were measured. In this study, vitamin D concentration below10 ng/ml was considered as vitamin D deficiency, 20-30 ng/ml as insufficiency, and 30-100 ng/ml as vitamin D sufficient. Data were analyzed by using SPSS version 22.Result : Out of 1523 patients 69.5% were women and 30.5% men. Urban and rural distribution was 63.16% and 36.84% respectively. Among the participants vitamin D deficiency was 54%, 35.8% vitamin D insufficient, and only 9.8% had normal level of vitamin D, regarding age specific deficiency highest 71.8% was in 71-80 years age group. Out of 1058 female 39.5% were vitamin D deficient, 45.6% had insufficient vitamin D level. Only 14.9% female were found normal level. Age specific deficiency found highest 63.8% in 61-70 year age group. On the other hand out of 465 male participants, 24% were vitamin D deficient, 34% were insufficient and 42% had normal level vitamin D. Highest deficiency 42.5% found in age group 61-70years. Conclusion :Considering the study result deficiency was higher among female than male. In female vitamin D deficiency increased after age of 31year. Vitamin D deficiency found highest in old age and middle age group. Over all age specific deficiency found significantly highest in 71 -80 years. In both male and female Vitamin D deficiency was found highest above 61years of age.

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“…The mean 25(OH)D in the study subjects was 25. 16 [18]. In another study in Dhaka, hypovitaminosis D (≤40 nmol/L) was observed in 77.7% of 121 women aged 18 -60 years [19].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D Status in Primary Hypothyroid Subjects Attending a Specialized Endocrine Center of Bangladesh

Paul¹,

Kamrul-Hasan²,

Prasad³

2019

OJEMD

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Background: Association between vitamin D deficiency and hypothyroidism has been reported by many authors though the study results are mixed. Objective: The study was conducted to observe vitamin D status among primary hypothyroid subjects. Materials/Methods: In this single-center cross-sectional study, 356 subjects with primary hypothyroidism (either new or previously diagnosed) were evaluated for serum thyroid stimulating hormone (TSH) and 25(OH) vitamin D levels. 25(OH)D levels were classified as normal (≥30 ng/ml), insufficient (>20 to 29.9 ng/ml), and deficient (≤20 ng/ml). Results: The mean age of the study subjects was 36.33 (±12.44) years; majority of them were female (89.9%), homemaker (79.8%), residing in urban or suburban areas (64%), and literate (85.7%); almost half (48%) of them were obese. Their median TSH was 6.17 µIU/ml and mean 25(OH)D was 25.16 (±12.18) ng/ml. The frequencies of vitamin D deficiency and insufficiency were 39.6% and 34.3% respectively. No statistical differences were observed in 25(OH)D levels between males and females, obese and non-obese, new cases and previously diagnosed cases, new cases with subclinical and overt hypothyroidism, the previously diagnosed cases with controlled and uncontrolled hypothyroidism, and among subjects living in urban, suburban and rural areas. Serum 25(OH) vitamin D level showed no correlations with age, body mass index (BMI) and TSH levels of the study subjects. Conclusion: The observed frequency of hypovitaminosis D (deficiency and insufficiency) was high (73.9%) in primary hypothyroid subjects from Bangladesh.

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Study of Serum Vitamin D Level in Different Socio-Demographic Population - A Pilot Study

Abstract: Conclusions: Vitamin D status was associated with a number of socio-demographic variables. Knowledge of these variables may improve targeted education and public health initiatives.

Cited by 26 publications

References 14 publications

Vitamin-D in Nepal: are we really vitamin-D deficient?

Vitamin-D in Nepal: are we really vitamin-D deficient?

A study on vitamin D level among the patients attending in a private chamber in Dhaka city

Vitamin D Status in Primary Hypothyroid Subjects Attending a Specialized Endocrine Center of Bangladesh

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