1999
DOI: 10.1016/s0140-6736(05)74871-6
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Subclinical coeliac disease in schoolchildren from northern Sardinia

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Cited by 61 publications
(31 citation statements)
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“…This suggests an increase in the recognition of milder histologic alterations by the Dutch physicians as part of the spectrum of CD, as introduced by Marsh 9 in 1992. However, even if the recognition of childhood CD has significantly increased in the Netherlands in recent years, population screening studies in our country 3,4 and in other countries [10][11][12][13][14] have shown frequencies of unrecognized CD of 1:300 to 1:100. There is a great difference between the frequency of clinically detected CD and that found after screening.…”
Section: Discussionmentioning
confidence: 99%
“…This suggests an increase in the recognition of milder histologic alterations by the Dutch physicians as part of the spectrum of CD, as introduced by Marsh 9 in 1992. However, even if the recognition of childhood CD has significantly increased in the Netherlands in recent years, population screening studies in our country 3,4 and in other countries [10][11][12][13][14] have shown frequencies of unrecognized CD of 1:300 to 1:100. There is a great difference between the frequency of clinically detected CD and that found after screening.…”
Section: Discussionmentioning
confidence: 99%
“…It may be that there is no strong association between CD and infertility, and these prior studies have succumbed to a type I error, attributing a difference when one did not truly exist. Alternatively, because there is a genetic component to CD, as demonstrated by the high rate of this disease in certain ethnic groups (15) or in family members (7,16), the rate of CD may be lower in Northern California due to its heterogeneous ethnic mix.…”
mentioning
confidence: 99%
“…Girls seem generally to be Th1 deviated, in contrast to boys which seem to be more Th2 deviated [155,156]. In many affected individuals CD remains undiagnosed, but the rate of diagnosis is increasing due to the frequent screening for the disease [142,143,[157][158][159][160][161][162][163]. Thus, screening studies are an important tool for detection of asymptomatic CD, which confers reduced risks for long term complications.…”
Section: Epidemiologymentioning
confidence: 99%