Subcutaneous blood pressure monitoring with an implantable optical sensor

Theodor, Michael; Ruh, Dominic; Fiala, Jens; Förster, Katharina; Heilmann, Claudia; Manoli, Yiannos; Beyersdorf, Friedhelm; Zappe, Hans; Seifert, Andreas

doi:10.1007/s10544-013-9768-6

Cited by 28 publications

(8 citation statements)

References 13 publications

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“…For the extracorporeal calibration of an implant, we recommend to at least monitor the patient over a period of 24 h to cover a large blood pressure range. The error of the calibration method and the blood pressure range will influence the accuracy of the system, as described in [24]. …”

Section: Measurement Resultsmentioning

confidence: 99%

Implantable Impedance Plethysmography

Theodor

Ruh

Ocker

et al. 2014

Sensors

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Section: Measurement Resultsmentioning

confidence: 99%

Implantable Impedance Plethysmography

Theodor

Ruh

Ocker

et al. 2014

Sensors

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“…[ 14 ] To date, most systems are composed of capacitive sensors, remote power sources, and RF coils. Large strides have been made in the implantable cardiovascular pressure sensors, such as the tube‐based implantable blood pressure sensor with a graphene‐based inline (Figure 8c), [ 236 ] the subcutaneous blood pressure monitoring with an implantable optical sensor, [ 237 ] and the implantable blood flow sensing system with a pressure sensor, an inductively powered wireless sensor interface and a RF coil integrated on a flexible circuit are developed (Figure 8d). [ 238 ]…”

Section: Device Configurations and Applicationsmentioning

confidence: 99%

“…[14, [235][236][237][238] Bladder pressure sensors Overcoming the inaccuracy and infections in the common catheter-based method.…”

Section: Semi-implantable Cochlear Systemsmentioning

confidence: 99%

Materials and Biomedical Applications of Implantable Electronic Devices

Liu

et al. 2022

Adv Materials Technologies

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The implantable electronic devices have attracted great attention for solving clinical problems ranging from monitoring psychological states to electro‐organ transplantation. The ongoing challenges are the selection of suitable materials in a target device configuration for biomedical applications. To address the ongoing challenges, there are several interesting questions: what types of electronic materials can be used as the implantable electrodes? What types of materials can be used as the substrates for the implantable electronic devices? What types of materials can be used as membranes and encapsulations? What types of device configurations are there for implantable biomedical applications? What types of applications are for implantable electronic devices? This review will highlight the attempts for addressing these questions. This review will explore the fundamentals and practical aspects of a variety of materials and their biomedical applications in implantable electronic devices. It is anticipated that this review could provide new opportunities for the construction of future implantable electronic devices, as well as related applications for disease diagnosis and therapy.

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“…These often consist of two units: a sensor unit to monitor the physiologically relevant signals such as blood pressure, and a control unit to perform A/D conversion, signal processing, and transmitting. In an implantable optical sensor for long-term blood pressure measurement [ 34 , 35 ], the correlation between pulse transit time and blood pressure was employed with light-emitting diodes (LEDs) and a silicon photodetector on a polyimide substrate. All of the substrates and sensors were encapsulated with silicone to achieve sensor conformability to the underlying tissues.…”

Section: Traditional Materials Used In Implantable Bioelectronicsmentioning

confidence: 99%

Advances in Materials for Recent Low-Profile Implantable Bioelectronics

et al. 2018

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The rapid development of micro/nanofabrication technologies to engineer a variety of materials has enabled new types of bioelectronics for health monitoring and disease diagnostics. In this review, we summarize widely used electronic materials in recent low-profile implantable systems, including traditional metals and semiconductors, soft polymers, biodegradable metals, and organic materials. Silicon-based compounds have represented the traditional materials in medical devices, due to the fully established fabrication processes. Examples include miniaturized sensors for monitoring intraocular pressure and blood pressure, which are designed in an ultra-thin diaphragm to react with the applied pressure. These sensors are integrated into rigid circuits and multiple modules; this brings challenges regarding the fundamental material’s property mismatch with the targeted human tissues, which are intrinsically soft. Therefore, many polymeric materials have been investigated for hybrid integration with well-characterized functional materials such as silicon membranes and metal interconnects, which enable soft implantable bioelectronics. The most recent trend in implantable systems uses transient materials that naturally dissolve in body fluid after a programmed lifetime. Such biodegradable metallic materials are advantageous in the design of electronics due to their proven electrical properties. Collectively, this review delivers the development history of materials in implantable devices, while introducing new bioelectronics based on bioresorbable materials with multiple functionalities.

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Subcutaneous blood pressure monitoring with an implantable optical sensor

Cited by 28 publications

References 13 publications

Implantable Impedance Plethysmography

Implantable Impedance Plethysmography

Materials and Biomedical Applications of Implantable Electronic Devices

Advances in Materials for Recent Low-Profile Implantable Bioelectronics

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