Subdural hemorrhage: A unique case involving secondary vitamin K deficiency bleeding due to biliary atresia

Miyao, Masashi; Abiru, Hitoshi; Ozeki, Munetaka; Kotani, Hirokazu; Tsuruyama, Tatsuaki; Kobayashi, Naho; Omae, Tadaki; Osamura, Toshio; Tamaki, Keiji

doi:10.1016/j.forsciint.2012.04.018

Cited by 12 publications

(9 citation statements)

References 28 publications

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“…In the majority of instances of traumatic acute subdural hemorrhage, the forces involved are sizeable, at least in the young and physically robust, with typical scenarios including motor vehicle accidents, falls, assaults, sporting events, and industrial accidents (12). However, other nontraumatic causes have been described, including neoplasia (13), sepsis (14), coagulation disorders (15, 16), high altitude (17), intracranial hypotension (13), and of course extension of hemorrhage from another intracranial source—such as ruptured aneurysms, vascular malformations, and intracerebral bleeds. Some researchers, notably in the field of infantile neuropathology, have also suggested that blood may ooze directly from the dura in the setting of the combination of hypoxic brain damage, brain swelling, and elevated central venous pressure (5 –7, 9, 18)—though this is not without controversy.…”

Section: Discussionmentioning

confidence: 99%

Non-Traumatic Acute Subdural Hemorrhage Due To Cranial Venous Hypertension

Orde¹

2019

Academic Forensic Pathology

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Acute subdural hemorrhage is typically associated with a history of head trauma, and as such it is a finding with significant potential medicolegal consequences. In this article, 37 adult and post-infantile pediatric sudden death autopsy cases with small volume (“thin film” or “smear”) acute subdural hemorrhage are presented—in which there is either no further evidence of head trauma or only features of minor head injury. The possible underlying pathophysiological mechanisms are explored, and it is concluded that a common thread in many of these cases is likely to have been cranial venous hypertension at around the time of death. These findings may have implications in instances where small volume subdural hemorrhage is identified in the absence of other evidence of significant head injury.

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Section: Discussionmentioning

confidence: 99%

Non-Traumatic Acute Subdural Hemorrhage Due To Cranial Venous Hypertension

Orde¹

2019

Academic Forensic Pathology

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“…Earlier reports of infants with a vitamin K deficiency hemorrhage secondary to cholestasis have been made. However, these infants had either not received vitamin K prophylaxis [ 4 ] or a lower dose [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…It acts as a cofactor for an enzyme that converts glutamyl residues in several coagulation factors (II, VII, IX, X). Therefore, hemorrhage results from a coagulopathy caused by a decrease in vitamin K-dependent coagulation factors [ 5 ]. Coagulation studies showed decreased activity in factors from the extrinsic pathway (factor VII), which resulted in a prolonged PT, as well as a prolonged aPTT due to deficient factor IX.…”

Section: Discussionmentioning

confidence: 99%

Hemorrhagic Diathesis as the Presenting Symptom of Neonatal Cholestasis

Faverey

Vandenplas

2014

Pediatr Gastroenterol Hepatol Nutr

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A 4-week-old infant presented with a coagulation disorder resulting from a vitamin K deficiency. The vitamin K deficiency was caused by neonatal cholestasis due to biliary atresia. Jaundice, hepatomegaly and pale stools are the predominant presenting symptoms of biliary atresia, none of which were recognized in our patient before admission. However, the patient presented with bleeding caused by vitamin K deficiency. She was fully breastfed and had received adequate doses of vitamin K at birth and from the age of 1 week. In case of a hemorrhagic diathesis due to neonatal cholestasis, timely identification of treatable underlying disorders, in particular biliary atresia, is important because an early surgical intervention results in a better prognosis. Meticulous history taking and a thorough physical exam can be decisive for an early diagnosis and subsequent intervention.

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“…Faktor risiko untuk APD antara lain tidak adanya profilaksis vitamin K saat lahir, ASI eksklusif, diare kronik dan penggunaan antibiotik berkepanjangan. 9 Penelitian berbasis rumah sakit berikut dilakukan untuk mengetahui profil klinis, faktor risiko dan luaran pasien dengan perdarahan intrakranial terkait APCD.…”

Section: Pendahuluanunclassified

Gambaran Pengetahuan Bidan dan Perawat Tentang VKDB di Puskesmas Prabumulih Sumatera Selatan

Utami

Yunus

Utami

2021

arteri

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Intracranial hemorrhage is a dangerous bleeding in infants. The impact of intracranial bleeding is in the form of death and sequelae, such as hydrocephalus, cerebral atrophy, encephalopathy, and epilepsy which will interfere with growth and development. One of the causes of intracranial bleeding is bleeding due to Vitamin K deficiency (VKDB). Meanwhile, intracranial bleeding due to vitamin K deficiency can be prevented by giving vitamin K1 to newborns. This study aimed to know the description of the level of knowledge of health workers about spontaneous intracranial bleeding caused by vitamin K deficiency bleeding at the Prabumulih Health Center, South Sumatra in 2020. The type of research used in this research is descriptive with a cross sectional design. The samples used in this study were nurses and midwives who worked at the Prabumulih Health Center in South Sumatra who had met the criteria in this study. The result showed that the frequency of sufficient knowledge of respondents was found as many as 31 people with a percentage of 46.3%. In conclusion Midwives at the Prabumulih health center in South Sumatra have a sufficient level of knowledge about intracranial bleeding due to vitamin K deficiency. It is hoped that this study can provide information to the public about the knowledge of intracranial bleeding due to vitamin K deficiency, so that the incidence of intracranial bleeding due to vitamin K deficiency and infant mortality can be reduced.

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Subdural hemorrhage: A unique case involving secondary vitamin K deficiency bleeding due to biliary atresia

Cited by 12 publications

References 28 publications

Non-Traumatic Acute Subdural Hemorrhage Due To Cranial Venous Hypertension

Non-Traumatic Acute Subdural Hemorrhage Due To Cranial Venous Hypertension

Hemorrhagic Diathesis as the Presenting Symptom of Neonatal Cholestasis

Gambaran Pengetahuan Bidan dan Perawat Tentang VKDB di Puskesmas Prabumulih Sumatera Selatan

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