We give a review of both our own original scientific results of the development of superconducting receivers for sub-terahertz astronomy and the main leading concepts of the global instrumentation. The analysis of current astronomical problems, the results of microwave astroclimate research, and the development of equipment for sub-terahertz radio astronomy studies justify the need and feasibility of a major infrastructure project in Russia to create a sub-terahertz telescope, as well as to enhance the implementation of the ongoing Millimetron and Suffa projects. The following results are discussed: i) superconducting coherent receivers and broadband subterahertz detectors for space, balloon, and ground-based radio telescopes have been developed and tested; ii) ultrasensitive receiving systems based on tunnel structures such as superconductorinsulator -superconductor (SIS) and superconductor -insulator -normal metal -insulatorsuperconductor (SINIS) have been created, fabricated, and examined; iii) a receiving array based on SINIS detectors and microwave readout system for such structures has been implemented; iv) methods for manufacturing high-quality tunnel structures Nb/AlO x /Nb and Nb/AlN/NbN based on niobium films with a current density of up to 30 kA/cm 2 have been developed. Receivers operated at 200 to 950 GHz and having a noise temperature only a factor of 2 to 5 higher than the quantum limit have been created and tested.