Subungual squamous cell carcinoma mistaken for a verruca

Robinette, Joel; Day, F.; Hahn, Paulette

doi:10.7547/87507315-89-8-435

Cited by 16 publications

(10 citation statements)

References 4 publications

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“…Presenting symptoms include paronychia, ingrown nail, dyschromia of the nail plate, bleeding, and pain 22 . Clinically, the disease may mimic onychomycosis, chronic paronychia, warts, epidermoid cyst, pyogenic granuloma, subungual exostosis, or malignant melanoma 3,8,10,15,20 . Subungual keratoacanthomas also pose a difficult differential diagnosis, not only clinically, but also radiologically and histopathologically, mimicking a well‐differentiated SCC 20 .…”

Section: Discussionmentioning

confidence: 99%

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Subungual Squamous Cell Carcinoma of the Toe: Report on Three Cases

2004

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Section: Discussionmentioning

confidence: 99%

“…PRIMARY TUMORS of the nail bed may be either in situ 1 or invasive 2–16 squamous cell carcinomas (SCC) or malignant melanomas 17 . Verrucous carcinomas 18,19 and keratoacanthomas 20 have also been described.…”

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confidence: 99%

Subungual Squamous Cell Carcinoma of the Toe: Report on Three Cases

2004

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“…SCC requires differential diagnosis with other pathological entities (tumoural and non‐tumoural), amongst which the ones worthy of being highlighted are hypertrophic actinic keratosis, keratoacanthoma, verruca vulgaris, basal cell carcinoma, seborrheic keratosis, verrucous dyskeratoma, follicle tumours of the sebaceous glands, eccrine poroma, as well as ulcers with vascular, neurological and infectious aetiology. Differential diagnosis with benign lesions like verruca vulgaris must be taken into account, as much for the similar appearance of both lesions as because a benign papillomatous lesion can mask SCC . In other cases, it may present in nails altered by other processes, for example, psoriasis, which makes diagnosis difficult.…”

Section: Discussionmentioning

confidence: 99%

Subungual squamous cell carcinoma and exostosis in third toe – case report and literature review

Valero

Gallart

González

et al. 2013

Acad Dermatol Venereol

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“…[20,[55][56][57][58] Monodactylous longitudinal erythronychia has been a presenting nail finding associated with either an invasive squamous cell carcinoma or squamous cell carcinoma in situ (Bowen disease) in at least seven individuals. Indeed, fungal and or bacterial cultures of the nail and surrounding tissue can also be positive for pathogenic organisms in patients with a concurrent subungual cancer.…”

Section: Squamous Cell Carcinomamentioning

confidence: 99%

Longitudinal Erythronychia

Cohen

2011

American Journal of Clinical Dermatology

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Longitudinal erythronychia is a linear red band on the nail plate that originates at the proximal nail fold, traverses the lunula, and extends to the free edge of the nail plate. Longitudinal erythronychia is classified based upon the number of nails affected and the number of red streaks present on each nail as follows: type Ia (monodactylous - single band), type Ib (monodactylous - bifid bands), type IIa (polydactylous - single band), and type IIb (polydactylous - multiple bands). Associated morphologic findings that can be present at the distal tip of the nail with longitudinal erythronychia include fragility, onycholysis, splinter hemorrhage, splitting, subungual keratosis, thinning, and V-shaped nick. Some patients with longitudinal erythronychia seek medical evaluation because of pain in the associated distal digit; however, the linear red nail plate dyschromia is often asymptomatic and the individual is concerned about the cosmetic appearance or distal nail fragility. Longitudinal erythronychia can be a clinical manifestation of an underlying local or systemic condition. Benign tumors (glomus tumor, onychopapilloma, and warty dyskeratoma), malignant neoplasms (malignant melanoma and squamous cell carcinoma), and other conditions (hemiplegia and postsurgical scar) can be associated with monodactylous longitudinal erythronychia or it may be idiopathic or the initial stage of polydactylous longitudinal erythronychia-associated systemic conditions. Polydactylous longitudinal erythronychia is most commonly reported in patients with Darier disease (keratosis follicularis); other associated conditions include acantholytic dyskeratotic epidermal nevus, acantholytic epidermolysis bullosa, acrokeratosis verruciformis of Hopf, amyloidosis, graft-versus-host disease, lichen planus, and pseudobulbar syndrome. Polydactylous longitudinal erythronychia has also been observed as an idiopathic finding. Biopsy of the nail matrix and nail bed may be necessary to establish the diagnosis of a longitudinal erythronychia-associated condition. Indeed, a biopsy should be seriously considered in patients aged more than 50 years who present with a monodactylous longitudinal red band to exclude squamous cell carcinoma. Treatment of longitudinal erythronychia depends on the etiology. For patients with longitudinal erythronychia-associated discomfort or severe nail splitting, a surgical excision may provide not only the underlying diagnosis of the nail dyschromia, but also relief of related symptoms.

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Subungual squamous cell carcinoma mistaken for a verruca

Cited by 16 publications

References 4 publications

Subungual Squamous Cell Carcinoma of the Toe: Report on Three Cases

Subungual Squamous Cell Carcinoma of the Toe: Report on Three Cases

Subungual squamous cell carcinoma and exostosis in third toe – case report and literature review

Longitudinal Erythronychia

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