Sugammadex-induced anaphylaxis involving sudden onset of severe abdominal pain

Matsumura, Tomoka; Mitani, Shigeki; Fukayama, Haruhisa

doi:10.1016/j.jclinane.2019.04.012

Cited by 6 publications

(6 citation statements)

References 3 publications

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“…The sudden onset of severe abdominal pain after the intake of MSG in this patient is similar to that of the clinical presentation of drug‐induced anaphylaxis 25 . Abdominal pain is classified as a grade 1 systemic allergic reaction 26 .…”

Section: Discussionsupporting

confidence: 68%

“… 8 MSG is an artificial food additive, and its clinical characteristics are similar to those of a drug. 25 In this patient, her allergy to MSG seemed to be desensitized by IHC and tolerance of MGS was obtained. From a therapeutic perspective, IHC therapy is a nonallergen‐specific immunotherapy.…”

Section: Discussionmentioning

confidence: 70%

“…The sudden onset of severe abdominal pain after the intake of MSG in this patient is similar to that of the clinical presentation of drug‐induced anaphylaxis. 25 Abdominal pain is classified as a grade 1 systemic allergic reaction. 26 Thus, PEC may also be considered a separate allergic disease entity that involves only the gastrointestinal tract and is mediated by histamine, and it appears to be one of many clinical manifestations of anaphylaxis.…”

Section: Discussionmentioning

confidence: 99%

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Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex

Kim

Noh

2023

Clinical Case Reports

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Section: Discussionsupporting

confidence: 68%

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex

Kim

Noh

2023

Clinical Case Reports

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“…The remaining 23 records were analyzed in-depth and their references explored. [ 9 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 ]…”

Section: Resultsmentioning

confidence: 99%

Sugammadex and anaphylaxis

Bora

Şahin

Özdoğan

2021

Journal of Anaesthesiology Clinical Pharmacology

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In this study, the published sugammadex-induced anaphylaxis reports were reviewed to determine similarities in their presentation during anesthesia. PubMed was searched for sugammadex-induced anaphylaxis without time limitation. Reports were evaluated if they were in English and met the criteria of anaphylaxis determined by the World Allergy Organization. Two independent reviewers extracted and assessed the data using predesigned data collection forms. In total, 23 suitable articles were found and 33 sugammadex-induced anaphylaxis cases were included in the study. The mean age was 43.09 years (from 3–89 years) and 17 (51.5%) of the patients were female. Considering all reported cases, the average onset time of anaphylaxis was 3.08 min, with a median of 3 min (range 1–8 min). The most common signs and symptoms were hypotension, tachycardia, erythema, and desaturation. Of the 20 patients who underwent confirmatory skin testing, 15 had a positive skin reaction for sugammadex. Epinephrine was not given when indicated in about 25% of cases. Sugammadex-induced anaphylaxis onset time was less than 5 min in 92.3% of all the reported cases. Rapid diagnosis and early recognition of signs and symptoms of anaphylaxis are essential for a favorable prognosis. Treatment needs to be started as soon as possible to ensure the best outcome for the patient.

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“…Most of the anaphylactic reactions occured within 4-5 minutes after intravenous infusion, and the most common symptoms are rash, edema, hypotension, tachycardia, abnormal respiratory sounds, and anaphylaxis [17,31]. However, sometimes these reactions develop late in the recovery room, and there are reports that non-specific reactions, such as abdominal pain, have preceded anaphylaxis [32]; hence, caution is always required while using sugammadex. The treatment of anaphylaxis caused by sugammadex is no different from that induced by other allergens [31,33].…”

Section: Hypersensitivity and Anaphylaxismentioning

confidence: 99%

A short review of adverse events of sugammadex

Son

Jeong

2022

Med Biol Sci Eng

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Sugammadex is a specific reversal agent that causes fast and reliable recovery from aminosteroidal non-depolarizing neuromuscular blocking agents. In addition, sugammadex does not cause muscarinic side effects that occur while using existing acetylcholinesterase inhibitors, and it is increasingly used in clinical practice despite its high price. However, with the accumulation of clinical experience, side effects such as hypersensitivity, anaphylaxis, tachycardia, severe bradycardia, hypotension, cardiac arrest, incomplete reversal, negative pressure pulmonary edema, coagulation disorder, steroid interaction, hypermagnesemia, hypothermia, vomiting, dry mouth, and nerve damage, are known to occur, and other adverse negative reactions have been reported. As BRIDION ® 's patent on sugammadex expires, generic products having lower prices are pouring into the market, and it is expected that these products will be used by anesthesiologist in clinical practice more than now. This review article focuses on the things that an anesthesiologist must keep in mind before using sugammadex widely.

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Sugammadex-induced anaphylaxis involving sudden onset of severe abdominal pain

Cited by 6 publications

References 3 publications

Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex

Treatment of primary eosinophilic colitis using immunoglobulin/histamine complex

Sugammadex and anaphylaxis

A short review of adverse events of sugammadex

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