Sunburn and Its Prevention

Abstract

SUMMAkV!hc discovery, approxifualely a century a\<(), o/ the role played by solar nlfraviolel railiation in delertuinin^ the state of the skin's heail/i. nuich proi^ress has been made in guiuini; a more exact iinderstandinii of the relationship which exists between .\kiii and sun. In this review there has been an attempt to trace the discoveries thai have been made towards interpreting the physical and chemical reactions responsible for the ileveh'j'nu'Ut of ultraviolet erythema in the skin. Consideration has been i^iven to such factors as the intensity and duration of radiation, the specific wavelcnf^tlis involved, the mechanism of the inflammatory response and the relative susceptibility of difjerent skin types. Other forms of skin damai^e in relation to solar erythema are also considered. the development and comparative efjeclivcness of the body's natural defence .systems af^ainst this erythema has been discassed in so far as prcseni l<nowled}if of these aspects is concerned. The ii.se, protective ability and methods of evaluation of sunscreen prej)arations have also been considered. The nccessiry for iisini,' these preparations on a daily basis is stressed.

Sarcoidosis and Mycobacterium avium-intracellulare cutaneous abscesses

“…Such differences are likely to have resulted, in part, from environmental factors. In particular, substantial variation may have occurred in the concentration of surrounding foliage and buildings which provide shade not only from direct sunlight, but also from skylight which comprises a significant part of global ambient UVR (Groves, 1980). The gardener in study A tended the grassed playing fields of a school, where little shade was afforded.…”

“…However, during the early 1970s Bencards Limited developed a technique for growing D. pieronyssinus on denatured non-ectodermal mammalian medium in large quantities. The availability of this culture made it possible to purify the major allergen, antigen Pi (Chapman & Platts-Mills, 1978, 1980. Antigen Pi is a glycoprotein of molecular weight 24,000 daltons which is very rapidly soluble in aqueous solution.…”