Sunscreen tests: Correspondence between in vitro data and values reported by the manufacturers

Skin photoprotection improvement: Synergistic interaction between lipid nanoparticles and organic UV filters

“…There are different reports on the quantity of a sunscreen formulation that needs to be applied in order to reach a good correlation between in vivo and in vitro results regarding SPF (Bimczok et al, 2007;Ferrero et al, 2002;Garoli et al, 2008Garoli et al, , 2009Heinrich et al, 2004). Besides the applied quantity, the measured SPF depends also on the formulation type (Heinrich et al, 2004).…”

Evaluation of Sun Protection Factor of Cosmetic Formulations by a Simple Visual In Vitro Method Mimicking the In Vivo Method

“…However, VitroSkin R and other artificial skins mimicking the epidermis are diffuse layers by themselves, thus generating a double diffuse interface when a film of sun protection formulation is deposited on the top. In all cases, more or less light will pass through but modeling the pathway of the electromagnetic radiation, as well as the photophysical and photochemical processes taking place within each layer and at the interfaces, becomes more and more difficult as the complexity of the system increases, as discussed by Garoli et al 26 Thus, in vitro prediction of cosmetic formulation SPFs is not an easy task. As discussed above, many factors can influence the results starting from the type and photostability of the sunscreens, the formulation and the complex absorption/scattering/ reflection processes taking place at the sun protector/artificial skin system, and the actual response of the photodetector as compared with the human skin erythema efficiency spectrum.…”

About Suncare Products

“…Even though they are able to be used in research, they seem to be quite unsuitable for industrial use [61]. Skin substitutes (Vitroskin ® ) provide an interesting analogy with real skin, but they are expensive and they have a limited length of use once they have been rehydrated [62]. Different synthetic substrates are currently used, such as polyvinylchloride film (Saran Wrap ® ), Teflon [63] and polymethylmethacrylate (PMMA) [64,65].…”