Superior long-term stability of a glucose biosensor based on inserted barrel plating gold electrodes

Hsu, Chao-Chun; Hsiao, Hung-Chan; Fang, Mei-Yen; Zen, Jyh‐Myng

doi:10.1016/j.bios.2009.07.028

Cited by 12 publications

(6 citation statements)

References 27 publications

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“…This concept showed superior stability up to 2.5 years at 25°C. Results indicated that the GOX/barrel plating gold biosensing platform is suitable for long‐term accurate glycemic control . Other article reports the advantages of incorporating an iron in a carbon paste electrode containing GOX.…”

Section: Biosensors For Important Markers Analysismentioning

confidence: 99%

“…This biosensor was fabricated by inserting two barrel plating gold electrodes onto an injection-molding plastic base followed by immobilizing with a bio-reagent layer and membrane. This concept showed superior stability up to 2.5 years at 25 • C. Results indicated that the GOX/barrel plating gold biosensing platform is suitable for long-term accurate glycemic control (20). Other article reports the advantages of incorporating an iron in a carbon paste electrode containing GOX.…”

Section: Glucosementioning

confidence: 99%

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Application of Electrochemical Biosensors in Clinical Diagnosis

Monošík

Stredansky

Šturdı́k

2012

Clinical Laboratory Analysis

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Analyses in the clinical area need quick and reliable analytical methods and devices. For this purpose, biosensors can be a suitable option, whereas they are constructed to be simple for use, specific for the target analyte, capable of continuous monitoring and giving quick results, potentially low-costing and portable. In this article, we describe electrochemical biosensors developed for clinical diagnosis, namely for glucose, lactate, cholesterol, urea, creatinine, DNA, antigens, antibodies, and cancer markers assays. Chosen biosensors showed desirable sensitivity, selectivity, and potential for application on real samples. They are often designed to avoid interference with undesired components present in the monitored systems.

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Section: Biosensors For Important Markers Analysismentioning

confidence: 99%

Section: Glucosementioning

confidence: 99%

Application of Electrochemical Biosensors in Clinical Diagnosis

Monošík

Stredansky

Šturdı́k

2012

Clinical Laboratory Analysis

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“…Most second-generation blood glucose sensors use ferrocene derivatives [13], ferricyanide (FIC), [14,15,16] and hydroquinone (HQ) [17] as a mediator for GOx to receive the electron of glucose oxidation [18,19,20,21,22,23,24,25]. These mediators assume the role of oxygen molecules, oxidizing the reduced-form flavin adenine dinucleotide (FADH 2 ) of GOx.…”

Section: Introductionmentioning

confidence: 99%

Effect of Poly-l-Lysine Polycation on the Glucose Oxidase/Ferricyanide Composite-Based Second-Generation Blood Glucose Sensors

Lin

Chang³

2019

Sensors

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Second-generation glucose biosensors are presently the mainstream commercial solution for blood glucose measurement of diabetic patients. Screen-printed carbon electrodes (SPCEs) are the most-used substrate for glucose testing strips. This study adopted hydrophilic and positively charged α-poly-l-lysine (αPLL) as the entrapment matrix for the immobilization of negatively charged glucose oxidase (GOx) and ferricyanide (FIC) on SPCEs to construct a disposable second-generation glucose biosensor. The αPLL modification is shown to facilitate the redox kinetics of FIC and ferrocyanide on the SPCEs. The SPCEs coated with 0.5 mM GOx, 99.5 mM FIC, and 5 mM αPLL had better sensitivity for glucose detection due to the appreciable effect of protonated αPLL on the promotion of electron transfer between GOx and FIC. Moreover, the SPCEs coated with 0.5 mM GOx, 99.5 mM FIC, and 5 mM αPLL were packaged as blood glucose testing strips for the measurement of glucose-containing human serum samples. The glucose testing strips had good linearity from 2.8 mM to 27.5 mM and a detection limit of 2.3 mM. Moreover, the 5 mM αPLL-based glucose testing strips had good long-term stability to maintain GOx activity in aging tests at 50 °C.

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“…Glucose biosensors, as miniaturized devices that can provide rapid and sensitive detection of glucose, have been playing important roles in diabetes diagnosis and management for the past several decades [1,2]. The development of next-generation glucose biosensors has been attracting increasing attentions [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Biosensing measurement of glucose: comparing a potentiostat and a source measure unit for signal generation

et al. 2019

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A: Over the past several decades since the invention of the first biosensor based on the Clarkoxygen electrode for glucose, the instrument most used for measuring for biosensor devices has been the potentiostat, and there have been thousands of published papers on electrochemical biosensors using the potentiostat. Here, we show for the first time a comparison between a potentiostat and a source measure unit (SMU) for signal generation in a biosensing measurement of glucose. The results demonstrated that both a potentiostat and a SMU could provide excellent sensing performances, though the results were slightly difference. We expect that this work can open up exciting opportunities for fundamental studies on the measurement methods of biosensing devices, as well as for a variety of applications for using biosensing devices in healthcare, environmental monitoring, and defense. K: Detector design and construction technologies and materials; Detector alignment and calibration methods (lasers, sources, particle-beams) 1Corresponding author.

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Superior long-term stability of a glucose biosensor based on inserted barrel plating gold electrodes

Cited by 12 publications

References 27 publications

Application of Electrochemical Biosensors in Clinical Diagnosis

Application of Electrochemical Biosensors in Clinical Diagnosis

Effect of Poly-l-Lysine Polycation on the Glucose Oxidase/Ferricyanide Composite-Based Second-Generation Blood Glucose Sensors

Biosensing measurement of glucose: comparing a potentiostat and a source measure unit for signal generation

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