Superplasticity of fine-grained magnesium alloys for biomedical applications: A comprehensive review

Savaedi, Zeinab; Motallebi, Reza; Mirzadeh, Hamed; Aghdam, Rouhollah Mehdinavaz; Mahmudi, R.

doi:10.1016/j.cossms.2023.101058

Cited by 35 publications

(7 citation statements)

References 273 publications

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“…Although strength can be attributed to several factors such as grain size, presence, and distribution of secondary phases, here, the alloying content and proportion of both the α-Mg and β-Li phases also play a role. Several thermomechanical techniques such as extrusion, equal channel angular pressing (ECAP), and friction stir process (FSP) improve the strength and ductility of Mg alloys, but Mg-Li alloys tend to possess very good elastic and superplasticity, especially in the duplex phase [19].…”

Section: Strength and Ductilitymentioning

confidence: 99%

Mg-Li-Based Alloys as Implant Materials

Okafor,

Munroe

2024

Biomedical Engineering

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This chapter is aimed at discussing the prospect of using novel magnesium-lithium-based alloys for temporary implantation. It discusses the challenges of implant materials and focuses on the design, characterization, and assessment of Mg-Li-Zn-Ca alloys. Biodegradable magnesium alloys have recently been the material of choice for the manufacture of implantable medical devices because they proffer efficacious solutions to temporary implantation. Magnesium-lithium-based alloys are a unique system of alloys that offer enhanced ductility and uniform degradation. The increase of lithium in the quaternary Mg-Li-Zn-Ca system resulted in phase transformation of the hcp crystal structure of magnesium to bcc, thus improving ductility. Lithium promoted the formation of a solid solution and a compact surface oxide that decreased corrosion kinetics in biological media. The alloys exhibited good biocompatibility, as evidenced by cell viability and metabolic activity when exposed to solutions retrieved from immersion tests. Furthermore, the improvement in mechanical properties and degradation properties of these alloys relative to other magnesium-based alloys provide an opportunity for wider adoption in the biomedical field.

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Section: Strength and Ductilitymentioning

confidence: 99%

Mg-Li-Based Alloys as Implant Materials

Okafor,

Munroe

2024

Biomedical Engineering

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“…The corrosion tests were performed with Hank's solution at body temperature (37 ± 0.5 °C) and at a pH of about 7. 4. The open circuit potentials (Eocp) of the coated Mg samples were initially monitored until they attained a steady-state potential.…”

Section: In-vitro Corrosion Testsmentioning

confidence: 99%

“…Firstly, magnesium has high biocompatibility and no toxic effects on the body. Additionally, magnesium alloys have a low density, making them lightweight, and they have excellent mechanical properties [4]. Therefore, they are very promising for use in implants and other orthopedic applications.…”

Section: Introductionmentioning

confidence: 99%

Surface Modification of Pure Mg for Enhanced Biocompatibility and Controlled Biodegradation: A Study on Graphene Oxide (GO)/Strontium Apatite (SrAp) Biocomposite Coatings

et al. 2023

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Magnesium alloys have excellent biodegradability but suffer from high corrosion rates and unfavorable biological responses. Thus, a surface modification strategy to regulate the corrosion rate and enhance biocompatibility is required. In this study, pure Mg substrate surfaces were coated with strontium apatite (SrAp) and graphene oxide (GO) biocomposite structures using the hydrothermal method to increase the biocompatibility of the surface of the Mg and obtain a moderate biodegradation rate. The effect of the GO concentration (0, 2, 4, and 6 wt.%) on the surface microstructure and its corrosion behavior were systematically studied. The corrosion behavior of the coatings was characterized in-vitro using the electrochemical polarization method in Hank’s solution. An EDS-connected SEM was used to examine the coatings’ surface properties. The functional groups of the coatings were identified using ATR-IR spectroscopy. To determine the degree of crystallization and examine the elemental distribution of the coatings, an XRD was used with a grazing incidence attachment. The XRD and SEM-EDS results showed that increasing the GO ratio in the SrAp-based coatings significantly enhanced the phase composition with the homogeneity and crystallinity, and the ATR-IR spectroscopy revealed that the SrAp/GO coatings were rich in functional groups, including hydroxyl, phosphate, and carbonate groups, that are known to promote bone formation and regeneration. The results of the electrochemical polarization tests demonstrated a considerable decrease in the corrosion rates of SrAp matrix coatings with the addition of GO. Additionally, the coatings containing GO exhibited higher polarization resistance (Rp) values, indicating their potential as a promising surface modification technique for biodegradable implants. These findings suggest that incorporating GO into the SrAp coatings could enhance their biocompatibility and provide a moderate biodegradation rate, which is desirable for biomedical applications.

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“…Magnesium and its alloys are promising biomedical materials due to their high mechanical properties, complete biodegradability and good biocompatibility [1][2][3]. Among all the Mg products, Mg alloy wires that can be used to produce sutures, staples, woven stents for the digestive tract or blood vessels, etc., have shown more widespread application potential [4,5].…”

Section: Introductionmentioning

confidence: 99%

Microstructural and Textural Evolution of Cold-Drawn Mg–Gd Wires during Annealing Treatment

Sun,

Bai,

Xue

et al. 2024

Materials

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In addition to cold drawing, the process of annealing is also essential in the preparation of Mg-4.7 wt%Gd (G4.7) alloy wires. The effect of annealing treatment on the recrystallized microstructure and texture of cold-drawn G4.7 wires was investigated. The results demonstrate that the uniformity and regularity of the recrystallized grains, as well as the annealing texture, impact the follow-up cold drawing performance. When the as-drawn G4.7 wires were annealed at 375 °C, the recrystallized grains were refined, accompanied by uniformity and regularity. Accordingly, the G4.7 wire had a good subsequent drawing deformability, with a maximum accumulative true strain (ATS) of 144%. Additionally, the evolution of the microstructure was consistent with the evolution of the texture. While annealing at a lower temperature (325 °C), the {0002} basal texture of the G4.7 wire was weak, forming the main texture component <101¯0>//DD (the drawing direction). With the increase in temperature, the basal texture was gradually strengthened and the texture component transformed from <101¯0>//DD to a recrystallized texture based on <112¯0>//DD. Even under high-temperature annealing, the G4.7 wire was still affected by the cold-drawn deformation texture and could not fully recover to the as-extruded texture, thus causing a decrease in the subsequent drawing performance.

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Superplasticity of fine-grained magnesium alloys for biomedical applications: A comprehensive review

Cited by 35 publications

References 273 publications

Mg-Li-Based Alloys as Implant Materials

Mg-Li-Based Alloys as Implant Materials

Surface Modification of Pure Mg for Enhanced Biocompatibility and Controlled Biodegradation: A Study on Graphene Oxide (GO)/Strontium Apatite (SrAp) Biocomposite Coatings

Microstructural and Textural Evolution of Cold-Drawn Mg–Gd Wires during Annealing Treatment

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