Surface Energies of Borosilicate Glass Surfaces Modified with n-Alkyl Silane Coupling Agents via Dynamic Contact Angle Measurements

Park, Joung-Man N; Kim, Jin Hak

doi:10.1006/jcis.1994.1398

Cited by 33 publications

(15 citation statements)

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“…The longest alkyl chain surfaces (C10, C14, and C18) exhibited advancing contact angles (95°-100°) consistent with data published by Park et al 24,26 ; however, several other groups 21,25,27,29 reported higher contact angles (105°-110°) for long chain alkyl surface layers. Dissimilarities in substrate, substrate cleaning methods, contact angle technique, solvent selection, etc., may account for such discrepancies.…”

Section: Discussionsupporting

confidence: 84%

Alkylsilane-modified surfaces: Inhibition of human macrophage adhesion and foreign body giant cell formation

Jenney

Anderson

1999

J. Biomed. Mater. Res.

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A homologous set of alkylsilane-modified glass surfaces with chain lengths ranging from methyl to octadecyl was prepared in order to examine the influence of alkyl surface chemistry on macrophage adhesion and foreign body giant cell (FBGC) formation. Contact angle and X-ray photoelectron spectroscopy analysis confirmed our silanation technique and indicated a consistent alkyl chain density independent of chain length. Human peripheral blood monocytes were isolated and cultured on these alkylsilane surfaces for a period of 10 days. The initial density of human monocytes was similar on all surfaces. Beyond day 0 the clean glass, methyl (DM and C1), propyl (C3), and hexyl (C6) surfaces maintained a high cell density and supported macrophage development. In contrast, long-term macrophage density was extremely low on the tetradecyl (C14) and octadecyl (C18) surfaces. When interleukin-4 was added to induce FBGC formation in vitro, the DM, C1, C3, and C6 surfaces supported high levels of macrophage fusion while clean glass strongly inhibited fusion. The C14 and C18 surfaces did not contain sufficient macrophages to support FBGC formation. Cage implant studies revealed that in vivo macrophage density and FBGC formation on clean glass and C6 surfaces was similar to in vitro data. In contrast to the monocyte culture results, the C18 cage implant samples supported significant FBGC formation, possibly as a result of different conditions within each experimental system. Radiotracer adsorption studies of eight human serum proteins identified the high concentration and tenacious hold of adsorbed von Willebrand factor as being possibly involved in the poor long-term macrophage density observed on C14 and C18.

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Section: Discussionsupporting

confidence: 84%

Alkylsilane-modified surfaces: Inhibition of human macrophage adhesion and foreign body giant cell formation

Jenney

Anderson

1999

J. Biomed. Mater. Res.

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“…By mixing the above two solutions with proper ratios, we obtained the modification solutions with desired mole fraction of C18 in total silanes (C18 + PEG). The membrane filters were incubated in the modification solution for 1 h, followed by rinsing with toluene, acetone, and deionized (DI) water. , All membrane filters were conditioned in relevant buffer before use.…”

Section: Methodsmentioning

confidence: 99%

“…The membrane filters were incubated in the modification solution for 1 h, followed by rinsing with toluene, acetone, and deionized (DI) water. 30,31 All membrane filters were conditioned in relevant buffer before use.…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

Microscopic Movement of Slow-Diffusing Nanoparticles in Cylindrical Nanopores Studied with Three-Dimensional Tracking

et al. 2016

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To study slow mass transport in confined environments, we developed a three-dimensional (3D) single-particle localization technique to track their microscopic movements in cylindrical nanopores. Under two model conditions, particles are retained much longer inside the pores: (1) increased solvent viscosity, which slows down the particle throughout the whole pore, and (2) increased pore wall affinity, which slows down the particle only at the wall. In viscous solvents, the particle steps decrease proportionally to the increment of the viscosity, leading to macroscopically slow diffusion. As a contrast, the particles in sticky pores are microscopically active by showing limited reduction of step sizes. A restricted diffusion mode, possibly caused by the heterogeneous environment in sticky pores, is the main reason for macroscopically slow diffusion. This study shows that it is possible to differentiate slow diffusion in confined environments caused by different mechanisms.

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“…Hydroxy(polyethyleneoxy)propyltriethoxysilane (PEG‐silane) (Gelest, MW:350‐750) was dissolved in 20 mL of anhydrous toluene to make a 1% PEG solution. The membrane filters were incubated in the modification solution for 1 h, followed by rinsing with toluene, acetone and DI water . All membrane filters were soaked in 25 mM phosphate buffer (pH ∼10) for 0.5 h before being exposed to the particle suspension.…”

Section: Methodsmentioning

confidence: 99%

Investigating axial diffusion in cylindrical pores using confocal single‐particle fluorescence correlation spectroscopy

Chen

Neupane

et al. 2016

Electrophoresis

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We explored the feasibility of using confocal fluorescence correlation spectroscopy to study small nanoparticle diffusion in hundred-nanometer-sized cylindrical pores. By modeling single particle diffusion in tube-like confined three-dimensional space aligned parallel to the confocal optical axis, we showed that two diffusion dynamics can be observed in both original intensity traces and the autocorrelation functions (ACFs): the confined two-dimensional lateral diffusion and the unconfined one-dimensional (1D) axial diffusion. The separation of the axial and confined lateral diffusion dynamics provides an opportunity to study diffusions in different dimensions separately. We further experimentally studied 45 nm carboxylated polystyrene particles diffusing in 300 nm alumina pores. The experimental data showed consistency with the simulation. To extract the accurate axial diffusion coefficient, we found that a 1D diffusion model with a Lorentzian axial collection profile needs to be used to analyze the experimental ACFs. The diffusion of the 45 nm nanoparticles in polyethyleneglycol-passivated 300 nm pores slowed down by a factor of ∼2, which can be satisfactorily explained by hydrodynamic frictions.

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Surface Energies of Borosilicate Glass Surfaces Modified with n-Alkyl Silane Coupling Agents via Dynamic Contact Angle Measurements

Cited by 33 publications

References 0 publications

Alkylsilane-modified surfaces: Inhibition of human macrophage adhesion and foreign body giant cell formation

Alkylsilane-modified surfaces: Inhibition of human macrophage adhesion and foreign body giant cell formation

Microscopic Movement of Slow-Diffusing Nanoparticles in Cylindrical Nanopores Studied with Three-Dimensional Tracking

Investigating axial diffusion in cylindrical pores using confocal single‐particle fluorescence correlation spectroscopy

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