The influence of oxygen on the wetting behavior of copper on single-crystal Al 2 O 3 has been studied. By controlling the oxygen partial pressure ( p O 2 ) and oxygen content in the copper simultaneously, contact angle can be varied between 125°and 22°. Evaluation of the Gibbs adsorption equation for the liquid/solid interface at 1300°C suggests that adsorption of a Cu-O complex at that interface plays a key role in promoting wetting. Formation of CuAlO 2 and dissolution of Al 2 O 3 in the melt also influence the contact angle, especially in the range of p O 2 > 10 −5 bar (1 Pa).