Surface modification of polyethylene film by acrylamide graft and alcoholysis for improvement of antithrombogenicity

Surface analysis of long-distance oxygen plasma sterilized PTFE film

“…Selectively adhered albumin is also exerted at the same time. As a result, platelets become less activated leading to less irreversible aggregation (with other platelets from blood) and pseudopodium [29]. Moreover, surface roughness has been generally acknowledged to be one of the factors contributing to material blood compatibility.…”

Novel pH- and Temperature-Sensitive Behavior of Binary Graft DMAEMA/PEGMEMA onto LDPE Membranes

“…Polyethylene (PE) has been applied widely in medical and biomedical fields in applications such as medical catheters, artificial blood vessels, and in some blood-contacting materials in extra corporeal circulation equipment during operations and so on. Like other synthetic polymers, a major problem in the use of PE in medical materials [6][7][8] is that its working surface is not compatible with blood and tends to initiate red-cell destruction and coagulation, consequently resulting in blood clots [9][10][11]. Chemical modification in the solid state is frequently carried out using radiation in order to produce surface oxidation [12].…”

Growth of hydrogel nano- and microlayers covalently bounded onto PE surface

“…PE is an attractive hydrophobic polymeric material for use as a hydrogel layer substrate due to its bulk properties. However, PE must be previously modified by the introduction of functional groups capable of acting as starting points in the synthesis of hydrogel materials and also of connecting the hydrophobic polymer and the hydrophilic layer [27][28][29][30]. A high density of carboxylic acid groups can be generated on the surface of PE by oxidization of the surface with chromic acid, as demonstrated by Whitesides and co-workers [31][32][33].…”