Surgical Interventions for Organ and Limb Ischemia Associated With Primary and Secondary Antiphospholipid Antibody Syndrome With Arterial Involvement

Hinojosa, Carlos A.; Anaya‐Ayala, Javier E.; Bermúdez-Serrato, Karla; García-Alva, Ramón; Laparra-Escareño, Hugo; Torres-Machorro, Adriana; Lizola, Rene

doi:10.1177/1538574417729273

Cited by 10 publications

(6 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meanwhile, these studies have also discussed that the potential mechanism of recurrent miscarriage as possibly being muscle damage caused by APL expression. Heparin can inhibit this pathogenic factor and is effective in the treatment of APS obstetrical diseases [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Effects of Comprehensive Nursing Based on Orem’s Self-Care Theory on Symptom Improvement and Pregnancy Outcome in Patients with Antiphospholipid Syndrome: A Retrospective Cohort Study

Meng

Bai

2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

Objective. A retrospective cohort study was conducted to explore the effects of comprehensive nursing based on Orem’s self-care theory on symptom improvement and pregnancy outcomes in patients with antiphospholipid syndrome (APS). Methods. Sixty patients with antiphospholipid antibody syndrome treated in our hospital from February 2019 to April 2021 were enrolled. The control group received comprehensive nursing, while the study group received comprehensive nursing based on Orem’s self-care theory. Nursing satisfaction, self-nursing ability, anxiety score, social support status, pregnancy outcome, and the score of life quality were compared between the two groups. Results. First of all, we compared the nursing satisfaction, the study group was very satisfied in 23 cases, satisfactory in 5 cases, general in 2 cases, the satisfaction rate was 100.00%. While in the control group, 11 cases were very satisfied, 10 cases were satisfied, 4 cases were general, and 5 cases were dissatisfied, the satisfaction rate was 83.33%. The nursing satisfaction in the study group was higher compared to the control group ( P < 0.05 ). Secondly, the self-concept, sense of self-care responsibility, self-nursing skills, health knowledge, and total score of the study group were higher compared to the control group ( P < 0.05 ). After intervention, the anxiety scores of the two groups decreased. Compared between the two groups, the anxiety scores of the study group before intervention and 1 week, 2 weeks, 3 weeks, and 4 weeks after intervention were lower compared to the control group ( P < 0.05 ). The comparison of social support showed that the scores of objective support, subjective support, utilization of support, and total score of social support in the study group were higher compared to the control group ( P < 0.05 ). The number of abortions in the control group was lower compared to the control group, and the number of full-term deliveries was higher compared to the control group ( P < 0.05 ). Finally, we compared the scores of life quality. After nursing, the scores of life quality of the two groups increased. Of note, the scores of physiological function, psychological function, social function, and health self-cognition in the study group were lower compared to the control group ( P < 0.05 ). Conclusion. Comprehensive nursing for patients with APS based on Orem’s self-care theory can effectively improve clinical symptoms and pregnancy outcome and play a positive role in facilitating patients’ nursing satisfaction and self-nursing ability, which can also effectively strengthen mental health and social support, this nursing model is worth popularizing in clinic.

show abstract

Section: Discussionmentioning

confidence: 99%

Effects of Comprehensive Nursing Based on Orem’s Self-Care Theory on Symptom Improvement and Pregnancy Outcome in Patients with Antiphospholipid Syndrome: A Retrospective Cohort Study

Meng

Bai

2022

Computational and Mathematical Methods in Medicine

View full text Add to dashboard Cite

show abstract

“…11 The patients with acute limb ischemia secondary to other underlying disease constitute a separate group. 8,12 In our case report, the patient presented with diffuse peritonitis being untimely diagnosed and complicated by acute arterial occlusion of the right lower limb. In case of severe endogenous intoxication, the cardiovascular system plays a critical role since the further course of the disease is determined by hemodynamic changes.…”

Section: Discussionmentioning

confidence: 79%

Acute lower limb ischemia secondary to diffuse peritonitis

Berek¹,

Kopolovets²,

Sihotský³

2020

Cor Vasa

View full text Add to dashboard Cite

Akútna ischémia dolných končatín je väčšinou spôsobená embóliou, trombózou a traumatickými zraneniami. Samostatnú skupinu tvoria pacienti so sekundárnou akútnou ischémiou končatín k inému základnému ochoreniu. Prezentácia kazuistiky: V tomto článku popisujeme kazuistiku 72-ročnej ženy, ktorá bola hospitalizovaná na Klinike cievnej chirurgie s akútnou ischémiou dolnej končatíny. Podľa predchádzajúcej anamnézy jeden deň pred hospitalizáciou pacientka bola vyšetrená chirurgom pre bolesť brucha: bez príznakov peritonitídy. Bola realizovaná ultrazvuková diagnostika brucha, kde sa nevyskytol žiaden akútny nález; podľa laboratorných testov boli zvýšené leukocyty na 18,2 × 10 9 /I. Nasledujúci deň pacientku doniesli na konzultáciu k cievnému chirurgovi kvôli bolesti a necitlivosti pravej dolnej končatiny. Vzhľadom na bolesť brucha a zvýšený počet leukocytov bola vykonaná v urgentnom režime CT angiografi a, na základe ktorej bolo diagnostikované pneumoperitoneum a akútny uzáver artérií pravej dolnej končatiny. Vykonaná simultanná emergentná operácia: trombektómia tepien dolných končatín a laparotómia, kde bola diagnostikovaná perforácia pylorusa, difúzna peritonitída. Bohužiaľ pacientka zomrela v dôsledku hemodynamického zhoršenia a rozvoja polyorganného zlyhania na základe septického šoku. Záver: Táto kazuistika predstavuje vývoj akútnej ischémie pravej dolnej končatiny ako komplikácie difúznej peritonitídy. Septický šok spôsobil dehydratáciu pacientky, zhoršenie hemokoagulačných parametrov a rozvoj sekundárnej trombózy artérií pravej dolnej končatiny.

show abstract

“…ET provokes thrombosis and haemorrhaging as typical vascular complications (Schafer 2006 ). ALI in thrombotic conditions such as APS and ET is rare, but often threatens limb viability (Hinojosa et al 2017 ; Ali et al 2009 ). Sub-acute or chronic limb ischaemia following sudden thrombotic artery occlusion can also be a serious state, and ischemic symptoms gradually worsen (Patel et al 2003 ).…”

Section: Discussionmentioning

confidence: 99%

Two effective cases of additional pedal artery angioplasty for severe lower limb ischemia following acute thrombotic artery occlusion with hypercoagulable state diseases

et al. 2020

View full text Add to dashboard Cite

Background Acute limb ischemia (ALI) and critical limb ischemia (CLI) following ALI are life-threatening diseases. The rare potential causes of ALI include hypercoagulable state diseases, such as antiphospholipid syndrome (APS) and essential thrombocythemia (ET). Hypercoagulability often make revascularization for arterial occlusion, especially associated with infrapopliteal lesions, difficult. This is because the vessels have poor run-off, and elevated peripheral vascular resistance associated with microcirculation failure, due to a high thrombus burden. There is no established treatment for this issue. Case presentation A 45 years-old and a 56 years-old male suffered from thrombotic arterial occlusion as a first manifestation of APS and ET, respectively. Combination therapy with aggressive anti-thrombotic therapy and revascularization, such as endovascular therapy and surgical thrombectomy based on the angiosome concept, was performed. However, the high thrombus burden caused a poor pedal outflow, and significant limb ischemia remained. Additional pedal artery angioplasty was performed to improve residual limb ischemia in each case and provided sufficient blood flow to the foot. Conclusion The pedal artery angioplasty for thrombotic pedal artery occlusion cases, associated with hypercoagulable state diseases, seems to be a treatment option for relieving residual limb ischemia.

show abstract

Surgical Interventions for Organ and Limb Ischemia Associated With Primary and Secondary Antiphospholipid Antibody Syndrome With Arterial Involvement

Cited by 10 publications

References 24 publications

Effects of Comprehensive Nursing Based on Orem’s Self-Care Theory on Symptom Improvement and Pregnancy Outcome in Patients with Antiphospholipid Syndrome: A Retrospective Cohort Study

Effects of Comprehensive Nursing Based on Orem’s Self-Care Theory on Symptom Improvement and Pregnancy Outcome in Patients with Antiphospholipid Syndrome: A Retrospective Cohort Study

Acute lower limb ischemia secondary to diffuse peritonitis

Two effective cases of additional pedal artery angioplasty for severe lower limb ischemia following acute thrombotic artery occlusion with hypercoagulable state diseases

Contact Info

Product

Resources

About