Surgical Management of Trauma-Related Intracranial Hemorrhage—a Review

Kvint, Svetlana; Gutierrez, Alexis; Blue, Rachel; Petrov, Dmitriy

doi:10.1007/s11910-020-01080-0

Cited by 9 publications

(14 citation statements)

References 141 publications

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“…Tumour removal by open surgery also provides information about the extent of involvement of nearby structures and helps reduce sampling errors during a stereotactic biopsy. In vascular pathology and trauma cases, open surgery provides good access to the severed vessel and the opportunity for brain decompression or necropsy [105,106,113]. The open approach means that the tissue samples taken are usually plentiful.…”

Section: Open Surgerymentioning

confidence: 99%

“…Less commonly, orbitozygomatic and transsphenoidal craniotomies are used, which provide better access to the skull base. Decompressive craniotomy for traumatic brain injury is a special entity that offers great exposure of brain areas, possible necrectomy in damaged areas, and relief of refractory increased intracranial pressure [113,115]. Craniotomy for superficial tumours typically encompasses the entire tumour area, whereas deep tumours can be reached through smaller craniotomies as the intracranial surgical field increases with a larger distance from the cranial bone surface [114].…”

Section: Open Surgerymentioning

confidence: 99%

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Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

et al. 2021

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In recent decades, cell biology has made rapid progress. Cell isolation and cultivation techniques, supported by modern laboratory procedures and experimental capabilities, provide a wide range of opportunities for in vitro research to study physiological and pathophysiological processes in health and disease. They can also be used very efficiently for the analysis of biomaterials. Before a new biomaterial is ready for implantation into tissues and widespread use in clinical practice, it must be extensively tested. Experimental cell models, which are a suitable testing ground and the first line of empirical exploration of new biomaterials, must contain suitable cells that form the basis of biomaterial testing. To isolate a stable and suitable cell culture, many steps are required. The first and one of the most important steps is the collection of donor tissue, usually during a surgical procedure. Thus, the collection is the foundation for the success of cell isolation. This article explains the sources and neurosurgical procedures for obtaining brain tissue samples for cell isolation techniques, which are essential for biomaterial testing procedures.

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Section: Open Surgerymentioning

confidence: 99%

Section: Open Surgerymentioning

confidence: 99%

Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

et al. 2021

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“…Prompt surgical hematoma evacuation is the preferred method of releasing intracranial pressure to prevent mortality 2,8–10 . However, craniotomy can cause collateral tissue damage, destroy the blood–brain barrier, induce interventricular pressure difference, and result in systemic immune/inflammatory effects 2 …”

Section: Introductionmentioning

confidence: 99%

“…Intracranial hematoma often results from hemorrhage caused by cerebrovascular disorder or craniocerebral trauma, and has high disability and mortality if no timely treatment is conducted. [1][2][3][4][5] Small hematoma can be managed without surgical treatment; however, large ones can lead to irreversible secondary brain injury if the hematomas could not be surgically evacuated in time,presumably via mass effect,excitotoxic edema,and progressive neurotoxicity. 6,7 Prompt surgical hematoma evacuation is the preferred method of releasing intracranial pressure to prevent mortality.…”

Section: Introductionmentioning

confidence: 99%

“…6,7 Prompt surgical hematoma evacuation is the preferred method of releasing intracranial pressure to prevent mortality. 2,[8][9][10] However, craniotomy can cause collateral tissue damage, destroy the blood-brain barrier, induce interventricular pressure difference, and result in systemic immune/inflammatory effects. 2 Minimally invasive techniques, including endoscopic approach, drilling, and drainage, have been tentatively used in stable patients with intracranial hematomas for its advantages of simple operation, less trauma and complications, easy to grasp, definite effect, and so on.…”

Section: Introductionmentioning

confidence: 99%

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A minimally invasive strategy to evacuate hematoma by synergy of an improved ultrasonic horn with urokinase: An in vitro study

Tang

Liao

et al. 2022

Medical Physics

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Objectives In this study, Ultrasound Needle—an improved minimally invasive ultrasonic horn device was used to explore its potential of synergizing with urokinase in enhancing clots lysis in an in vitro intracranial hematoma model. Materials and methods Ten milliliter bovine blood was incubated for 3 h at 37℃, and coagulated into clot to mimic intracranial hematoma in vitro. Ultrasound Needle was an improved ultrasonic horn with a fine tip (1.80 mm) and metallic sheath, and had a frequency of 29.62 kHz. The 10,000 IU urokinase was injected through the metallic sheath during the vibration of Ultrasound Needle tip to lyse the clots for 8 min under different working parameter settings (n = 8) to explore the influence of parameters Amplitude (%) and Duty (%) on clot lysis weight (W0). The maximum temperatures were measured by an infrared thermometer during the treatment process. The W0 of different treatment groups (US (Ultrasound Needle), US + NS (normal saline), UK (urokinase), US + UK, n = 8) were compared to verify the synergistic lysis effect of Ultrasound Needle combined with urokinase at optimal working parameters (40% Amplitude, 20% Duty; input power 4.20 W; axial tip‐vibration amplitude 69.17 μm). Clots samples after treatment were fixed overnight for macroscopic examination. And fluorescent frozen sections and scanning electron microscopy examination were performed to show microscopic changes in clots and evaluate the cavitation effect of Ultrasound Needle on promoting drug diffusion within the clots. Results The clot lysis weight W0 increased with the parameters Amplitude (%) and Duty (%), reached a peak (2.435 ± 0.137 g) at 40% Amplitude and 20% Duty (input power 4.20 W), and then decreased. Higher Amplitude (%) and Duty (%) led to higher maximum temperature, and W0 was negatively correlated with the maximum temperature after the peak (r = −0.958). At the optimal parameter setting, the maximum temperature was 33.8 ± 0.9℃, and the W0 of the US + UK group was more than four times of UK alone group (2.435 ± 0.137 g vs. 0.607 ± 0.185 g). Fluorescent frozen sections confirmed that the ultrasound energy of Ultrasound Needle could mechanically damage the clot tissues and promote the intra‐clots drug diffusion. Macroscopic examination showed that US + UK group caused larger clots lysis area than UK alone group (2.08 cm2 vs. 0.65 cm2). In addition, electron microscopy examination exhibited that the fibrin filaments of the clots in US + UK group were lysed more thoroughly compared to single treatment groups. Conclusions Ultrasound Needle, an improved ultrasonic horn device, can mechanically damage the clot tissues and exhibit an excellent synergistic lysis effect with thrombolytic drugs. Therefore, Ultrasound Needle has great potential in providing a new minimally invasive strategy for rapid intracranial hematoma evacuation.

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Cranial Acute and Subacute Subdural Hematomas

Kanat

2021

Subdural Hematoma

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Surgical Management of Trauma-Related Intracranial Hemorrhage—a Review

Cited by 9 publications

References 141 publications

Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

Neurosurgical Approaches to Brain Tissue Harvesting for the Establishment of Cell Cultures in Neural Experimental Cell Models

A minimally invasive strategy to evacuate hematoma by synergy of an improved ultrasonic horn with urokinase: An in vitro study

Cranial Acute and Subacute Subdural Hematomas

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