Surgical prophylaxis in familial adenomatous polyposis: do pre-existing desmoids outside the abdominal cavity matter?

Gibbons, Daniel C; Phillips, R. K. S.; Clark, Sue

doi:10.1007/s10689-010-9342-9

Cited by 8 publications

(4 citation statements)

References 22 publications

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“…A correlation with the familiar intestinal polyposis could be shown. Approximately 10-25% of the patients with polyposis present intra-or extra abdominal desmoid tumors 10 . But in our case, there is no correlation with the familial intestinal polyposis.…”

Section: Figure-2: Histopathological View Of Desmoid Tumor Discussionmentioning

confidence: 99%

Desmoid Tumor of the Abdominal Wall: A Case Report

Arzoo¹,

Akter²,

Afroz³

et al. 2023

Eastern Med. Coll. J.

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Desmoid tumors alternatively known as aggressive fibromatosis are benign myofibroblastic neoplasms originating from the muscle aponeurosis and classified as deep fibromatoses and these tumors are non-cancerous growth that occurs in the connective tissue. These tumors constitute 3% of all soft tissue tumors and 0.03% of all neoplasms and they occur usually between the age group of 20-40 years with a strong prevalence among women with fertile age group. In female patients presenting a tumor of the lower abdominal wall especially after cesarian section, an endometriotic tumor as well as an aggressive desmoid tumor should be considered. Symptoms in correlation with the monthly period can facilitate the presurgical differentiation between endometriosis and fibromatosis. Ultrasound reveals the typical location of both tumors and its remarkable sonographic appearance. In the clinical practice, the desmoid fibromatosis of the lower abdominal wall is a very rare disease. We present a case of a 19-year-old pregnant and discuss diagnostic and therapeutic options by literature review. With the knowledge of the prognosis of the desmoid fibromatosis and the respective treatment options including wait and see, complete surgical resection with macroscopically free margins and adjuvant approaches is essential to avoid further interventions and progression of the locally destructive tumor. EMCJ. July 2022; 7(2): 28-31

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Section: Figure-2: Histopathological View Of Desmoid Tumor Discussionmentioning

confidence: 99%

Desmoid Tumor of the Abdominal Wall: A Case Report

Arzoo¹,

Akter²,

Afroz³

et al. 2023

Eastern Med. Coll. J.

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show abstract

“…A correlation with the familiar intestinal polyposis could be shown [1]. Approximately 10–25% of the patients with polyposis present intra- or extra abdominal desmoid tumors [2]. Supposed risk factors of desmoids are previous surgical interventions, pregnancy and hormonal treatment with estrogen.…”

Section: Discussionmentioning

confidence: 99%

Desmoid Tumor of the Anterior Abdominal Wall in Female Patients: Comparison with Endometriosis

Krentel

Tchartchian²,

Wilde

2012

Case Reports in Medicine

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In female patients presenting a tumor of the lower abdominal wall especially after cesarian section, an endometriotic tumor as well as an aggressive desmoid tumor should be considered. Symptoms in correlation with the monthly period can facilitate the presurgical differentiation between endometriosis and fibromatosis. Ultrasound reveals the typical location of both tumors and its remarkable sonographic appearance. In the clinical practice, the desmoid fibromatosis of the lower abdominal wall is a very rare disease. We present a case of a 25-year-old pregnant and discuss diagnostic and therapeutic options by a PubMed literature review. With the knowledge of the prognosis of the desmoid fibromatosis and the respective treatment options including wait and see, complete surgical resection with macroscopically free margins and adjuvant approaches is essential to avoid further interventions and progression of the locally destructive tumor.

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“…The association between desmoid development and surgical wound healing in patients with FAP has long been established [45]. Presence of extra-abdominal and abdominal wall DTs increases the risk of intra-abdominal DT development at the time of prophylactic colon resection [46]. A recent case report analyzed the individual tumor mutations of a FAP patient with multiple recurrences at the same surgical site.…”

Section: Desmoid Cell Of Originmentioning

confidence: 99%

Extra-Abdominal Desmoid Tumors Associated with Familial Adenomatous Polyposis

Calvert

Monument

Burt

et al. 2012

Sarcoma

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Extra-abdominal desmoid tumors are a significant cause of morbidity in patients with familial adenomatous polyposis syndrome. Understanding of the basic biology and natural history of these tumors has increased substantially over the past decade. Accordingly, medical and surgical management of desmoid tumors has also evolved. This paper analyzes recent evidence pertaining to the epidemiology, molecular biology, histopathology, screening, and treatment of extra-abdominal desmoid tumors associated with familial adenomatous polyposis syndrome.

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Surgical prophylaxis in familial adenomatous polyposis: do pre-existing desmoids outside the abdominal cavity matter?

Cited by 8 publications

References 22 publications

Desmoid Tumor of the Abdominal Wall: A Case Report

Desmoid Tumor of the Abdominal Wall: A Case Report

Desmoid Tumor of the Anterior Abdominal Wall in Female Patients: Comparison with Endometriosis

Extra-Abdominal Desmoid Tumors Associated with Familial Adenomatous Polyposis

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