Survival and Morbidity in a Geographically Defined Population of Low Birthweight Infants

Powell, TeyrnonG.; Pharoah, PeterO.D.; Cooke, R W

doi:10.1016/s0140-6736(86)90893-7

Cited by 59 publications

(20 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Details of these assessments have been published. [15][16][17][18][19][20] For the purposes of this study, by measuring the head circumference in these children at birth, near term at discharge, and at 4 and 15 years of age, four periods of growth could be examined: antenatal, immediate postnatal, infancy, and early childhood. The occipitofrontal circumference (OFC) was extracted from the clinical record for each time point and converted into a standard deviation score (z score) taking in to account the sex and age at the time of measurement.…”

Section: Population and Methodsmentioning

confidence: 99%

Are there critical periods for brain growth in children born preterm?

Cooke

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

View full text Add to dashboard Cite

Background: Children born very preterm who attend mainstream schools have a high prevalence of minor motor, behavioural, and learning disorders. These appear to be associated with reduced postnatal growth, particularly of the head. It is unclear when this poor growth occurs and whether growth restriction during different periods has different effects on later function. Objective: To identify periods during early development, in children born preterm, when impaired head growth may influence minor motor and cognitive function. Population: A geographically defined cohort of 194 infants born in Merseyside during 1980-81 and weighing less than 1500 g. Methods: Measurements of head circumference (occipitofrontal circumference (OFC)) were available at birth, hospital discharge, 4 years, and 15 years of age. Assessments of intelligence (intelligence quotient (IQ)) and minor motor impairment (test of motor impairment (TOMI)) were made at 8 years of age. Clinical, social, and demographic variables were obtained from the clinical record and maternal interviews. Results: IQ correlated significantly with OFC at 4 and 15 years of age after correction for growth restriction at birth (intrauterine growth restriction (IUGR)) and social class. TOMI scores correlated significantly with OFC at all four times, but especially with OFC at discharge and with change in OFC between birth and discharge. They were not affected by correction for social class or IUGR. Conclusion: Although both IQ and minor motor impairments correlate strongly with each other at school age in very low birthweight children, the factors determining them and their timing of operation are different. Interventions designed to improve IQ in this population would need to reduce IUGR and improve later childhood growth. Those aimed to improve motor ability need to be targeted more at brain protection during the neonatal period.

show abstract

Section: Population and Methodsmentioning

confidence: 99%

Are there critical periods for brain growth in children born preterm?

Cooke

2005

Archives of Disease in Childhood - Fetal and Neonatal Edition

View full text Add to dashboard Cite

show abstract

“…The obstetric and neonatal records were abstracted for demographic and clinical details of mother and birth weight of the child. The children were examined at age 3 years18 and again at age 8 years19 to determine the prevalence of clinical disability. At the 8 year follow up of the index population, for those children attending normal school, an age and sex matched comparison from the same school was also assessed.…”

Section: Methodsmentioning

confidence: 99%

Dermatoglyphic patterns, very low birth weight, and blood pressure in adolescence

Stevenson

2001

Archives of Disease in Childhood - Fetal and Neonatal Edition

View full text Add to dashboard Cite

Aims-To test the null hypotheses that finger and palm prints have no relation with fetal growth or adolescent blood pressure. Methods-All 128 singleton, unimpaired, very low birth weight (VLBW; <1500 g) infants born to mothers resident in the county of Merseyside in 1980 and 1981 were studied retospectively. The comparison group consisted of 128 age, sex, and school matched children. Main outcome measures were blood pressure at age 15 years, birth weight ratio, fingerprint patterns, and palmar AtD angles. Results-The VLBW index population had a significantly higher systolic blood pressure than the comparison group (mean diVerence 3.2 mm Hg). The diVerence in diastolic blood pressure between the VLBW index and the matched comparison group was not significant. No significant diVerences were found in the palmar AtD angles or in the fingerprint proportions of arches, loops, and whorls and no correlation was found between fingerprint patterns and blood pressure. Among the VLBW index population, both height and right palmar AtD angle were independently and significantly correlated with and explained 12.1% of the variance in the systolic blood pressure. Birth weight ratio, as a measure of fetal growth restriction, had no significant correlation with systolic blood pressure. Conclusions-The higher systolic blood pressure of adolescents who were of very low birth weight compared with the matched comparison group is not associated with fingerprint patterns or birth weight ratio as markers for fetal growth restriction. (Arch Dis Child Fetal Neonatal Ed 2001;84:F18-F22)

show abstract

“…Especially the combination of these factors with early, abnormal neurological signs results in an unfavourable prognosis regarding neurodevelopmental and motor outcome, learning capabilities, and language acquisition [14,17,23,30,35]. GA, IVH, periventricular leucomalacia, bronchopulmonary dysplasia, socio-economic status, assisted ventilation and hyperbilirubinaemia are reported to be important neonatal risk factors [3,4,7,11,15,28,30,32].…”

Section: Discussionmentioning

confidence: 99%

Neonatal risk factors and risk scores including auditory evoked responses

Pasman

Rotteveel

Maassen

et al. 1998

European Journal of Pediatrics

View full text Add to dashboard Cite

This study shows that IVH, bilirubin and assisted ventilation contribute most to the validity and predictive value of the NBRS. Furthermore, regarding neurological outcome addition of a GAF in combination with an AERF resulted in a substantial improvement of the validity and predictive value. The shortcomings of the current neonatal risk scores require a careful interpretation of clinical perinatal data regarding the prediction of neurodevelopmental outcome in preterm infants.

show abstract

Survival and Morbidity in a Geographically Defined Population of Low Birthweight Infants

Cited by 59 publications

References 21 publications

Are there critical periods for brain growth in children born preterm?

Are there critical periods for brain growth in children born preterm?

Dermatoglyphic patterns, very low birth weight, and blood pressure in adolescence

Neonatal risk factors and risk scores including auditory evoked responses

Contact Info

Product

Resources

About