Survival Rates for Breast Cancer in Iranian Patients: a Meta-Analysis

Abstract

Background: Breast cancer is the most common cancer among Iranian women. Since development of the disease in Iranian women occurs relatively early, the survival rate matters considerably. In different countries, survival of breast cancer patients varies considerably. Therefore, the one-year, three-year, five-year, and tenyear survival rates for breast cancer in Iran were assessed using a meta-analysis. Materials and Methods: This systematic review and meta-analysis was based on valid Iranian sources including SID, MAGIRAN and IRANMEDEX, along with reliable English databases, namely, PUBMED and SCOPUS. In domestic databases, a search was conducted based on key words of breast cancer and survival rate, and in international databases, with "breast cancer" and the equivalent of "neoplasm" of Mesh Word, "survival rate" and "Iran." Then all reviewed papers and theses which met the inclusion criteria were selected for investigation. To conduct the analysis STATA 11.2 software and random-effects models were used. Results: In 24 studies, 22,745 participants were included. The one-year, three-year, five-year and ten-year survival rates were 0.956, 0.808, 0.695 and 0.559, respectively. The minimum and maximum survival rates for 5-years were 0.48 and 0.87. The average age of the onset of the disease was 48.3. Conclusions: As in Iran, since the onset of the disease is at low age, in spite of the relatively high survival rate as compared to other cancers, prevention and screening programs at early age for early stage diagnosis seems necessary.

Survival rates of patients with breast cancer in countries in the Eastern Mediterranean Region: a systematic review and meta-analysis

“…The survival rate of women with breast cancer in the Arab populations was lower than in the non-Arab populations in this Region. In a 2016 meta-analysis conducted in the Islamic Republic of Iran, the pooled 1-, 3-, 5-and 10-year survival rates in women were 95%, 80%, 69% and 55% respectively (31) and in a study from Jordan in 2010 the 1-, 3-and 5-year survival rates were 91%, 70% and 59% respectively (32), confirming the result of our study. The results of some studies indicate that Arab women with breast cancer may have a worse prognosis than other populations (33,34).…”

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“…5,6 Studies conducted in Iran's provinces over the past decade have estimated the 5-year survival rate in breast cancer patients to be 48%-87%. 7 These differences may be due to patients' biological, racial/ genetic, geographical, socioeconomic, and cultural differences, and also different treatment options and patients' access to these facilities.…”

Survival probability and prognostic factors of Iranian breast cancer patients using cure rate model

“…Breast cancer is the second cause of cancer mortality worldwide and the fifth cause of mortality in Iranian women . Based on the 2016 statistics, the 5‐year survival rate for breast cancer were 73% and 53% for the developed and developing countries respectively…”

“…In addition, the reported cases vary in different areas . Based on the increase in the incidence since 1990 in most countries and its increasing growth, especially at lower ages in Iran and its high treatment costs, the broad controlling programs are necessary to improve, prevent, and recognize the factors affecting the survival and use the health care budget optimally . Thus, this study aimed to investigating the survival rate and possible prognostic factors of the patients with breast cancer in Iran.…”