Swallow syncope after cardiac surgery in a sheep

Pritchette, Louella A.; Carty, Anthony J; Katz, Michael G.; Fargnoli, Anthony S.; Kirsch, Jennifer; Bridges, Charles R.

doi:10.1111/j.1532-950x.2013.12056.x

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2015

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“…One week later, the animal received gene therapy during cardiac surgery. Sedation, anaesthesia and post‐operative care were administered as previously described (Pritchette et al., ). On examination, it was found that a portion of the abomasum (fundus and body) protruded through a congenital diaphragmatic hernia in the Bochdalek foramen of the right side, causing slight lateral displacement of the heart.…”

Section: Resultsmentioning

confidence: 99%

Bochdalek Congenital Diaphragmatic Hernia in an Adult Sheep

Williams

Katz

Fargnoli

et al. 2015

Anat. Histol. Embryol.

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Summary Congenital diaphragmatic hernia (CDH) is a rare condition. The aetiology of CDH is often unclear. In our case, a hollow mass was noted on MRI. Cardiac ejection fraction was diminished (47.0%) compared to 60.5% (average of 10 other normal animals, P < 0.05). The final diagnosis of congenital diaphragmatic hernia (Bochdalek type) was made when the sheep underwent surgery. The hernia was right-sided and contained the abomasum. Lung biopsy demonstrated incomplete development with a low number of bronchopulmonary segments and vessels. The likely cause of this hernia was genetic malformation.

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Section: Resultsmentioning

confidence: 99%