Synchronous breast carcinoma and peritoneal mesothelioma

Abstract

Breast cancer may be associated with other primary cancers via germline mutations; however, sporadic occurrences of other malignancies are rare. With increased use of advanced breast cancer imaging, including MRI and PET/CT, other incidental synchronous cancers are increasingly identified. Such cases can represent unique diagnostic and treatment challenges. Here, we present a case of a young woman diagnosed with primary breast cancer who underwent imaging studies identifying an incidental primary peritoneal mesothelioma.

A Case Report of Mesothelioma Response to Endocrine Therapy in Synchronous Breast Cancer and Pleural Epithelioid Mesothelioma: A Double Exemestane Effect

“…However, here are some reports on metachronous mesothelioma following radiotherapy for the treatment of primary breast cancer. Breast cancer is the most common cancer among women and can be associated with other primary cancers via germline mutations, including BRCA1/BRCA2, and p53 [4][5][6][7]. To the best of our knowledge, this is the first published case of pleural malignant mesothelioma with synchronous breast cancer.…”

“…Due to the rarity of these tumours, there is still no consensus on the definitive treatment protocols. As a result, individualized treatment with multidisciplinary close follow-up might improve survival outcomes [4][5][6][7].…”

Challenges in the diagnosis and treatment of peritoneal mesothelioma: a case study and review of the literature

“…The literature describes cases of peritoneal mesothelioma resulting in small bowel obstruction [10] or infertility [11]. Other reports call attention to the simultaneous appearance of peritoneal mesothelioma along with endometriosis [12,13] or breast cancer [14]. In a study of 164 women diagnosed with peritoneal mesothelioma, the mean age of diagnosis was 49 years, and the most frequently reported symptom was abdominal or pelvic pain.…”