Synchronous hepatic metastasis and metachronous Krukenberg tumor from advanced colon cancer. A case report with an unexpected disease-free survival

G, Li Destri; Puzzo, Lidia; Russo, Alessia; Ferraú, Francesco; Cataldo, Antonio Di; Puleo, Stefano

doi:10.1016/j.ijscr.2016.11.044

Cited by 2 publications

(1 citation statement)

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“…Lam and Ong described a similar case of a 51-year-old Chinese woman with ovarian metastasis from unilateral right colon carcinoma, resected a year earlier and measuring 23 cm on the largest axis [8] . In contrast, Destri published a patient with KT after sigmoid carcinoma with hepatic metastasis, successfully resected [9] and Shiono published a bilateral KT case whose largest ovary was 23.5 cm on the largest axis, synchronous with right colon carcinoma [10] . As unilateral, the right ovary is the most frequently involved [5] , as in the present case.…”

Section: Discussionmentioning

confidence: 99%

Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Zogbi

Isaías

Machado

et al. 2017

International Journal of Surgery Case Reports

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HighlightsKrukenberg tumour (KT) is defined as a metastatic ovary carcinoma.KT is usually of gastric origin, but can be applied to metastatic tumors originating from carcinomas of other sites, such as the colon.Ovarian metastasis of the colorectal carcinoma is uncommon and, when it does occur, it tends to be synchronous, rather than metachronous.The immunohistochemical evaluation helps to distinguish primary ovarian carcinoma from metastatic carcinomas.

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Section: Discussionmentioning

confidence: 99%

Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Zogbi

Isaías

Machado

et al. 2017

International Journal of Surgery Case Reports

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Krukenberg Tumor: A Review of Prognostic Factors and Management

Zolezzi¹

2020

Onco Tum Res

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Aim: This review aims to summarize current evidence on Krukenberg Tumors (KT), addressing the main prognostic determinants and its’ management. Background: Krukenberg Tumors are rare metastatic tumors of the ovary. They were initially described by Friederich Ernst Krukenberg in 1896. They arise from extra-ovarian primary signet-ring cell carcinomas, being the gastrointestinal tract the most common site of origin. The most common clinical presentation of KT is an abdominal mass or discomfort in a premenopausal 40 to the 50-year-old woman. The prognosis is extremely poor compared to primary ovarian cancer. Results: Overall survival may vary significantly according to the choice and timing of treatment. The effective treatment strategies for KT are still controversial. However, therapeutic options include surgical resection as the mainstay of treatment when possible and the application of different Chemotherapy (CT) regimens. Conclusions: Several factors negatively affect prognosis: an incomplete metastasectomy, extensive disease at diagnosis and the origin of the tumor are the main factors that most authors agree incur in a worse prognosis. KT’s optimal therapeutic strategies are still a matter of debate, raising the need for more studies to achieve consensus.

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Synchronous hepatic metastasis and metachronous Krukenberg tumor from advanced colon cancer. A case report with an unexpected disease-free survival

Cited by 2 publications

References 15 publications

Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Krukenberg’s tumour unilateral giant metachronous of colonic origin – Case report

Krukenberg Tumor: A Review of Prognostic Factors and Management

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