SYNTAX Score and Outcomes of Coronary Revascularization in Diabetic Patients

Kundu, Amartya; Sardar, Partha; O’Day, Kevin; Chatterjee, Saurav; Owan, Theophilus; Abbott, J. Dawn

doi:10.1007/s11886-018-0971-1

Cited by 22 publications

(23 citation statements)

References 37 publications

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“…Both the prevalence and frequency of CAD increase in patients with diabetes compared to patients without diabetes. In many studies, it has been shown that CABG treatment in patients with DM and three-vessel disease gives better results in terms of prognosis of patients compared to PCI [ 10 , 11 ]. In our study, in support of these findings, DM was significantly higher in patients who were given a CABG decision than the group in which PCI was decided.…”

Section: Discussionmentioning

confidence: 99%

Comparison of SYNTAX and Gensini Scores in the Decision of Surgery or Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease

Boyraz¹,

Peker²

2022

Cureus

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Introduction: Many scoring systems have been developed to determine the extent of coronary artery disease (CAD) in patients with multi-vessel disease. The most widely used of these are Synergy between percutaneous coronary intervention with Taxus and cardiac surgery (SYNTAX) and Gensini scoring. Gensini scoring system can successfully show coronary plaque burden. In our study, we aimed to test the predictive power of SYNTAX and Gensini scores for surgical or percutaneous intervention decisions made by the cardiac team in patients with three-vessel disease.Methods: A total of 476 patients without ST-elevation myocardial infarction with the three-vessel disease were included in the study. SYNTAX and Gensini scores of the patients were calculated from their coronary angiographies. Receiver operating characteristic curve (ROC-curve) analysis was performed using both scores.Results: Both the SYNTAX score and Gensini score were able to predict heart team decisions (AUC: 0.759, 0.680; p<0.001). Diabetes and smoking were more common in patients who were decided to have surgery (p<0.001). Conclusion:In the light of our study results, the decisions to be made with the SYNTAX score will be closer to the decisions of the heart team than the Gensini score.

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Section: Discussionmentioning

confidence: 99%

Comparison of SYNTAX and Gensini Scores in the Decision of Surgery or Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease

Boyraz¹,

Peker²

2022

Cureus

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“…Но у больных с СД и ИБС достоверно чаще регистрировали дистальный тип поражения коронарного русла и изменения диффузного характера. В проведенном ранее исследовании с включением 1148 больных также было отмечено превалирование дистального коронаросклероза при СД 2 типа [22].…”

Section: Discussionunclassified

Сlinical and hemodynamic characteristics and coronary blood flow in patients with chronic coronary artery disease and type 2 diabetes

Марданов¹,

Kokozheva²,

Шукуров³

et al. 2021

Russ J Cardiol

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Aim. To assess the features of clinical and hemodynamic characteristics and the severity of coronary involvement in patients with chronic coronary artery disease (CAD) with and without diabetes.Material and methods. The study included 100 patients with stable CAD, which were divided into two groups: group I (mean age, 57,9-1,04 years, male/female 35/14) — 49 patients with CAD and type 2 diabetes, II — (60,2-0,9 years, 34/17) — 51 patients without SD. Along with behavioral and biological risk factors, clinical and hemodynamic characteristics were analyzed. All patients underwent coronary angiography.Results. The presence of diabetes in patients with CAD was associated with abdominal obesity and comorbidity of somatic diseases. Among group I patients, electrocardiographic signs of left ventricular hypertrophy, conduction abnormalities, accompanied by a decrease in the left ventricular ejection fraction, impaired diastolic function, and high mean pulmonary artery pressure were significantly more often detected. In patients with CAD and type 2 diabetes, significant right coronary artery (CA) stenoses were more often recorded (39%), while in patients without diabetes, the anterior descending artery was the most susceptible to atherosclerosis. In group I, stenosis of the distal CA third was detected 1,5 times more often (p<0,001), and their diffuse multivessel lesion prevailed by 28% (73% and 45%, respectively, p<0,005). The average SYNTAX score in patients with and without diabetes was 29,2±0,8 vs 22±0,7, respectively (p<0,0005).Conclusion. In patients with CAD and diabetes, more pronounced atherosclerotic coronary involvement (diffuse multivessel CAD) was revealed, which should be taken into account when planning further treatment. The risk of adverse cardiovascular events will always be present with percutaneous coronary interventions.

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“…To overcome the anatomical SYNTAX score's limitation of ignoring individual variation, the clinical variables, such as age, sex, ejection fraction, creatinine clearance, peripheral vascular disease, and chronic obstructive pulmonary disease, are introduced in the SYNTAX scoreⅡ, which greatly improves the score system's efficiency in predicting post-revascularization risk for complex CAD [23,24] . In 2017, He et al used the SYNTAX scoreⅡ to predict the risk of death following the left main coronary artery PCI.…”

Section: Syntax Score ⅱmentioning

confidence: 99%

“…Moreover, they found that the long-term mortality rates after PCI in the low, medium, and high SYNTAX score Ⅱ groups were 2.4%, 3.4%, and 11.6%, respectively (P < 0.0001) [25] , which was consistent with the findings of Xu et al [26] . In addition, the SYNTAX score Ⅱ can not only predict adverse events at 1 year [27] , 4 years [26,28] , 5 years [29][30][31] , and 10 years [31] after revascularization for complex CHD, such as major adverse cardiovascular events (MACE) [31,32] , MACCE [24,27] , no-reflow phenomenon [33] , all-cause mortality [26,31] , and others, but it also has a significant predictive value in a variety of hemodynamic settings, such as left main coronary artery [25,28,29,34] , multiple vessel diseases [29,30,34] , acute coronary syndrome [27,33] , cerebral infarction [35] , and cardiac valve disease [36] , and so on. Yang et al's study also confirmed that the SYNTAX score Ⅱ has a higher predictive value for revascularization in complex CAD than the anatomical SYNTAX score [risk ratio (RR):…”

Section: Syntax Score ⅱmentioning

confidence: 99%

Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease

Zhang

Zeng

Yang

et al. 2022

Chinese Medical Sciences Journal

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Complex coronary heart disease (CHD) has become a hot spot in medicine due to its complex coronary anatomy, variable clinical factors, difficult hemodynamic reconstruction, and limited effect of conservative drug treatment. Identifying complex CHD and selecting optimal treatment methods has become more scientific as revascularization technology has improved, and coronary risk stratification scores have been introduced. SYNTAX and its derivative scores are a decision-making tool that could quantitatively describe the characteristics of coronary lesions in patients based on their complexity and severity, could assist clinicians in rationalizing the selection of hemodynamic reconstruction treatment strategies, and have outstanding value in evaluating the prognosis of patients with complex CHD undergoing revascularization treatment. The authors hope that describing the practical application of SYNTAX and its derivative scores in complex CHD will deepen the understanding of the relationship between the choice of different revascularization strategies and SYNTAX and its derived scores in complex CHD and provide a further reference for clinical treatment of complex CHD.

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SYNTAX Score and Outcomes of Coronary Revascularization in Diabetic Patients

Cited by 22 publications

References 37 publications

Comparison of SYNTAX and Gensini Scores in the Decision of Surgery or Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease

Comparison of SYNTAX and Gensini Scores in the Decision of Surgery or Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease

Сlinical and hemodynamic characteristics and coronary blood flow in patients with chronic coronary artery disease and type 2 diabetes

Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease

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