Synthese der inaktiven Brasilsäure

The Chemistry of the Hydantoins.

“…Other solvents were also studied, and the optimum conditions for the reaction determined. The original Bergs procedure was used by Pfeiffer and his associates in the synthesis of a large number of hydantoin derivatives as intermediates in the preparation of new -amino acids (498,499,500,501,502,503,504). This procedure has also been followed in the syntheses of other hydantoins (129,484,569,576,577,578), but has in general been replaced by the simpler method developed by Bucherer. The Bucherer modification of the Bergs synthesis has been applied to a large number of carbonyl compounds of all types by Henze and his associates (5, 632).…”