Synthesis and antibacterial activity of oxazolidinones containing triazolyl group

Fan, Hui; Xu, Gang; Chen, Yilang; Jiang, Zhiteng; Zhang, Shuhua; Yang, Yushe; Ji, Ruyun

doi:10.1016/j.ejmech.2007.01.012

Cited by 33 publications

(10 citation statements)

References 17 publications

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“…Besides this, it is used as a component of veterinary medicines as well as a photographic developer . Fortunately, in synthetic organic chemistry, rongalite has found the application in installing SO 2 functionality into the organic molecules, which could be valuable precursors for many synthetic transformations viz alkenes could be generated from sulfones by using Ramberg‐Bäcklund as well as Julia olefination reactions which can be used for further functionalization to generate diversity in taxing molecules . Not only this, rongalite is an attractive building block to assemble sultine derivatives which are useful masked dienes partners for Diels‐Alder (DA) reaction to construct intricate molecules which are otherwise challenging or almost impossible by other means .…”

Section: Introductionmentioning

confidence: 99%

New Dimensions in Rongalite Chemistry: The Land of Opportunities in Organic Synthesis and Material Sciences

Ali

2020

ChemistrySelect

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Rongalite, first time reported in the chemical structure in 1905, also known as bruggolite or sodium formaldehyde sulfoxylate, having good solubility and stability in organic media, is not only a cheap and commercially available (in kg amount) reagent with a range of industrial applications for instance emulsion polymerization, an excellent decolouring agent, antioxidant in pharmaceutical development, and an antidote for heavy metals, but also used as an effective regents in a plethora of organic reactions particularly in redox reactions as a powerful reducing agent. More interestingly, in recent years, it has also shown its impact in material sciences for the preparation of CdTe, CoTe2, and Ag2Se thin films, nanowire networks, hollow nanospheres, copper nanoparticles (Cu‐Nps), CdTe‐quantum dots and so forth. Keeping in mind the importance of this vital reagent in both organic chemistry as well as in material sciences, herein I intended to report the recent developments along with a brief overview of old literature wherever necessary to showcase the utility of this valuable reagent. This particular review article not only covers the applications of this environmentaly benign reagent in organic synthesis but also its usefulness in material sciences in particular nanosciences has been exposed for the first time.

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Section: Introductionmentioning

confidence: 99%

New Dimensions in Rongalite Chemistry: The Land of Opportunities in Organic Synthesis and Material Sciences

Ali

2020

ChemistrySelect

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“…The result of in vitro antibacterial activity against a spectrum of resistant and susceptible Gram-positive organisms [ 66 ] clearly shows that all compounds ( Figure 29 ) bearing sulfonyl group have good antibacterial activity. Compound showed more potent antibacterial activity than linezolid and vancomycin.…”

Section: Structure Activity Relationship (Sar) [ 26 mentioning

confidence: 99%

Current Updates on Oxazolidinone and Its Significance

Pandit

Singla²,

Shrivastava

2012

International Journal of Medicinal Chemistry

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Oxazolidinone is a five-member heterocyclic ring exhibiting potential medicinal properties with preferential antibacterial activity. Scientists reported various synthetic procedures for this heterocyclic structure. Current review articles tried to cover each and every potential aspect of oxazolidinone like synthetic routes, pharmacological mechanism of action, medicinal properties, and current research activities.

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“…General procedure for the preparation of 3a-3i and 3j-3q (Fan et al, 2007;Boos et al, 2006;Girisha et al, 2009) Piperazine derivatives 3a-3i were prepared by the reaction of appropriate substituted sulfonamides (0.01 mol) and…”

Section: Synthesis Of 2a and 2bmentioning

confidence: 99%

Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives

Wang

Yang

et al. 2010

Med Chem Res

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A series of novel (R)(-)-1- [(4-chlorophenyl) phenylmethyl]piperazine derivatives were designed, synthesized, and tested for in vivo anti-allergic activities. Most of these derivatives exhibited significant effects on both allergic asthma and allergic itching. Three of the 19 piperazine derivatives (namely, 3d, 3i, and 3r) have stronger potency against allergic asthma than levocetirizine, the positive control drug. Meanwhile, in the test of allergic itching, five of the 19 compounds (namely, 3b, 3g, 3k, 3o, and 3s) have more potent activities than levocetirizine.

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Synthesis and antibacterial activity of oxazolidinones containing triazolyl group

Cited by 33 publications

References 17 publications

New Dimensions in Rongalite Chemistry: The Land of Opportunities in Organic Synthesis and Material Sciences

New Dimensions in Rongalite Chemistry: The Land of Opportunities in Organic Synthesis and Material Sciences

Current Updates on Oxazolidinone and Its Significance

Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives

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