Synthesis and antioxidant activity of zinc(II) phthalocyanine tetranitroxide

Korkut, Sıbel Eken; Ahmetali, Erem; Bilgi, Mesut; Karataş, Özgül; Yerli, Yusuf; Peksel, Ayşegül; Şener, M. Kasım

doi:10.1016/j.poly.2021.115045

Cited by 16 publications

(9 citation statements)

References 39 publications

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“…The connections between the substituent and the centrally located metal atom have a direct effect on the π electron density. 63 Özel et al (2016) indicated that water-soluble titanium(IV) Pc compounds demonstrated DPPH scavenging activity ranging from 5.12% to 43.14%. 17 Yıldırım et al (2017) reported that all tested Pc compounds displayed radical scavenging ability 64 Among the three Pc compounds, the highest antioxidant ability was obtained with compound 4 causing 60.06% DPPH radical scavenging inhibition.…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Novel axially symmetric and unsymmetric silicon(iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

et al. 2022

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Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Novel axially symmetric and unsymmetric silicon(iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

et al. 2022

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“…(2021) investigated the antioxidant activity of zinc phthalocyanine. The compound exhibited radical scavenging activity at all the tested concentrations and the percentage of the DPPH radical scavenging activity increased from 19.92 to 66.77 % as the concentration enhanced from 100 μg/mL to 500 μg/mL [34] . Günsel et al.…”

Section: Resultsmentioning

confidence: 98%

Effect of Axial Ligand Length on Biological and Anticancer Properties of Axially Disubstituted Silicon Phthalocyanines

Yenilmez

Farajzadeh

Kuşçulu

et al. 2023

Chemistry & Biodiversity

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In this study, three new axially disubstituted silicon phthalocyanines (SiPc1-3) and their quaternized phthalocyanine derivatives (QSiPc1-3) were prepared and characterized. The biological properties (antioxidant, antimicrobial, antibiofilm, and microbial cell viability activities) of the water-soluble silicon phthalocyanines were examined, as well. A 1 % DMSO diluted with pure water was used as a solvent in biological activity studies. All the compounds exhibited high antioxidant activity. They displayed efficient antimicrobial and antimicrobial photodynamic therapeutic properties against various microorganisms, especially Gram (+) bacteria. Additionally, they demonstrated high antibiofilm activities against S. aureus and P. aeruginosa. In addition, 100 % bacterial reduction was obtained for all the studied phthalocyanines against E. coli viable cells. Besides, the DNA cleavage and binding features of compounds (QSiPc1-3) were studied using pBR322 DNA and CT-DNA, respectively. Furthermore, the human topoisomerase I enzyme inhibition activities of compounds QSiPc1-3 were studied. Anticancer properties of the water-soluble compounds were investigated using cell proliferation MTT assay. They exhibited anticarcinogenic activity against the human colon cancer cell line (DLD-1). Compounds QSiPc1 and QSiPc3 displayed a high anticarcinogenic effect on the DLD-1 cell line. The obtained results indicated that all the studied compounds may be effective biological agents and anticancer drugs after further investigations.

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“…This activity has been attributed to the resonance of π-electrons in porphyrins and the central zinc ion, as well as reduction mechanism by the d z 2 orbital of the central copper ion. 23,24 Therefore, it was demonstrated that the Zn-PP cream had great potential as a broad-spectrum sunscreen, strongly preventing UV-A radiation.…”

Section: Resultsmentioning

confidence: 99%

Biobased sunscreen fabrication using Zn-porphyrins from engineered Corynebacterium glutamicum

Ko¹,

Oh²,

Han³

2023

Green Chem.

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Synthesis and antioxidant activity of zinc(II) phthalocyanine tetranitroxide

Cited by 16 publications

References 39 publications

Novel axially symmetric and unsymmetric silicon(iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

Novel axially symmetric and unsymmetric silicon(iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

Effect of Axial Ligand Length on Biological and Anticancer Properties of Axially Disubstituted Silicon Phthalocyanines

Biobased sunscreen fabrication using Zn-porphyrins from engineered Corynebacterium glutamicum

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