Synthesis and characterization of 4-(2-aminoethyl)aniline imprinted polymer as a highly effective sorbent of dopamine

Separation of octopamine racemate on (R,S)-2-amino-1-phenylethanol imprinted polymer – Experimental and computational studies

“…To investigate the applicability of MIP1 for separation of A1 from the complex samples, spiked human serum albumin was used and the previously optimized SPE protocol was employed [18]. The ability of MIP1 to the effective separation of A1 was compared with the extraction capabilities of NIP1, as well as with the commercial C18 sorbent.…”

“…Molecular imprinting of polymer matrices provides a straightforward procedure for obtaining the adsorbents with a desired complementarity to the chiral molecules [16,17]. In production of molecularly imprinted polymers (MIPs) the strategy that used the structural analog of analyte as the template while imprinting, provides advantage because it enables to avoid the bleeding of target analyte from the polymer matrix during the analysis [18]. Therefore, in the present studies (R,S)-2-amino-1-phenylethanol was selected as the structural analog of the target analyte (octopamine) in the imprinting process.…”

Development of a validated strategy for the determination of tryptamine in human cerebrospinal fluid in the presence of competitors using molecularly imprinted polymers

“…The monomer 1 was selected because of its nonacidic character as well as because of the presence of the aromatic ring. The acidic monomers 2 – 6 were selected because of our previous conclusion that the carboxylic group was able to form strong interactions with bioamine templates . The binding capacities, B of MIP 1 /NIP 1 –MIP 6 /NIP 6 , distribution coefficients K D , and IFs for tryptamine were determined according to the equations – and are presented in Table .…”

The selective response of a templated polymer for the cationic drug pentamidine: implications from molecular simulations and experimental data

“…The loading and washing steps were carried out according to previously optimized MISPE protocols for the hydrochlorides of biogenic amines. 24 However, the elution step with the ammonium acetate-methanol system was insufficient to quantitatively desorb the analyte. Thus, a formic acid-methanol (0.5 : 99.5 v/v) system was used as the eluent.…”