Synthesis and Characterization of Biocomposite BCP/Collagen for Bone Material Scaffold

Abstract

<p>Abstract<br />Biphasic calcium phosphate (BCP) widely used as implants and scaffolds in different orthopedic and dental application. The aim of this study was to determine synthesis and characteristics of biocomposite BCP/collagen as bone scaffold material. BCP/collagen was classified into three groups: 1) BCP/K5 (5% collagen in scaffold), 2) BCP/K10 (10% collagen in scaffold), and 3) BCP/K15 (15% collagen in scaffold). The samples were characterized by Fourier Transform Infrared (FTIR) Spectroscopy, and Scanning Electron Microscope (SEM) techniques. Overall, concentration of collagen was not significantly different to the spectrum. However, FTIR analysis shows the change intensity in bio-composite BCP/collagen. Collagen intensity Higher concentration when collagen concentration in scaffold higher. Morphology analysis of the scaffold showed significant differences in pore formation. BCP/K15 was showed pores formed in scaffold. Synthesis of composite BCP/collagen does not affect the spectrum of functional groups, but affects the formation of pores in the bone scaffold material.</p>

Sintesis dan Karakterisasi Kalsium Fosfat dari Cangkang Bekicot dengan Metode Presipitasi

“…Keramik biomaterial dapat dibentuk dengan prekusor kalsium dan fosfat [3]. Tulang hewan banyak dimanfaatkan sebagai prekusor kalsium dalam sintesis biomaterial.…”