Synthesis and characterization of biological macromolecules double emulsion based on carboxymethylcellulose/gelatin hydrogel incorporated with ZIF-8 as metal organic frameworks for sustained anti-cancer drug release

Pourmadadi, Mehrab; Aslani, Ali; Abdouss, Majid

doi:10.1016/j.ijbiomac.2023.125168

Cited by 14 publications

(1 citation statement)

References 85 publications

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“…28,29 Integration of ZIF-8 into hydrogel compositions offers improved mechanical strength, stability, and controlled release of drugs or biologically active compounds. 30 Additionally, ZIF-8 has been successfully employed in a GelMA-Z hydrogel that can be injected, demonstrating its biocompatibility and improved therapeutic efficacy. 31 It is worth noting that the sustained release of drug-loaded nanoparticles from injectable hydrogels has demonstrated promise in manipulating macrophage phenotype and advancing immune-regenerative medicine.…”

Section: Introductionmentioning

confidence: 99%

Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Xiao,

Zheng,

Wang

et al. 2024

Nanoscale Adv.

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Section: Introductionmentioning

confidence: 99%

Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Xiao,

Zheng,

Wang

et al. 2024

Nanoscale Adv.

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Recent Advances in Biomacromolecule‐Reinforced 2D Material (2DM) Hydrogels: From Interactions, Synthesis, and Functionalization to Biomedical Applications

Gu,

Cui,

et al. 2024

Adv Funct Materials

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Regenerative biomedicine has emerged as a forefront area in medical research, heralding a new era of therapeutic strategies. This review delineates the integration of 2D materials (2DMs) within the area of biomedical engineering, leveraging their superior physicochemical attributes for enhance biomedical outcomes. The synergistic interaction between biomacromolecules and 2DMs is explored, demonstrating their potential to mitigate the limitations inherent to each while simultaneously augmenting their beneficial properties. In particular, incorporating 2DMs into hydrogels highlights their capability to enhance the mechanical strength of hydrogels, providing a biomimetic scaffold for tissue engineering regeneration and cancer diagnosis and therapy. An overview of the synthetic methodologies are provided for 2DMs, elucidating their interaction dynamics with biomacromolecules. The review primarily concentrates on the applications of biomacromolecule‐reinforced 2DM hydrogels across various biomedical fields, including bone tissue engineering, wound healing, neural tissue engineering, cardiac tissue engineering, as well as in the delivery of drugs and genes, cancer therapy, and biosensing technologies. Finally, the review discusses the existing challenges and future outlook for developing and using biomacromolecule‐reinforced 2DM hydrogels, underlining their transformative potential in regenerative medicine.

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Nanocomposites Based on Metal–Organic Framework/Polysaccharide in Drug Delivery

Pooresmaeil,

Namazi

2024

Nanostructure Science and Technology

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Synthesis and characterization of biological macromolecules double emulsion based on carboxymethylcellulose/gelatin hydrogel incorporated with ZIF-8 as metal organic frameworks for sustained anti-cancer drug release

Cited by 14 publications

References 85 publications

Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Enhancing anti-angiogenic immunotherapy for melanoma through injectable metal–organic framework hydrogel co-delivery of combretastatin A4 and poly(I:C)

Recent Advances in Biomacromolecule‐Reinforced 2D Material (2DM) Hydrogels: From Interactions, Synthesis, and Functionalization to Biomedical Applications

Nanocomposites Based on Metal–Organic Framework/Polysaccharide in Drug Delivery

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