2010
DOI: 10.1039/c0cc00762e
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Synthesis and characterization of gold-deposited red, green and blue fluorescent silica nanoparticles for biosensor application

Abstract: Fluorescent silica nanoparticles deposited with highly monodisperse gold nanoparticles (1-2 nm) were synthesized via the W/O method and intensive ultrasound irradiation. A large surface area of gold-doped fluorescent silica nanoparticle serves as a platform to immobilize a specific binding protein for biomolecules interaction in bioimaging applications.

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Cited by 18 publications
(8 citation statements)
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“…Previously reported plastic-based immunosensors required a surface modification step for the immobilization of biomolecules. Among these methods, silanization using 3-aminopropyltriethyoxysilane (APTES) is a widely used method for coupling of biomolecules onto the inorganic substrate [ 18 ]. However, silane is difficult to react with organic materials without any hydroxyl groups present on the surface by using UV/ozone treatment [ 5 ].…”
Section: Resultsmentioning
confidence: 99%
“…Previously reported plastic-based immunosensors required a surface modification step for the immobilization of biomolecules. Among these methods, silanization using 3-aminopropyltriethyoxysilane (APTES) is a widely used method for coupling of biomolecules onto the inorganic substrate [ 18 ]. However, silane is difficult to react with organic materials without any hydroxyl groups present on the surface by using UV/ozone treatment [ 5 ].…”
Section: Resultsmentioning
confidence: 99%
“…To synthesize monodispersed SNP, previously reported W/O microemulsion method was employed [22]. Briefly, 43.2 g of Triton X-100, 180 mL of cyclohexane and 38.4 mL of n-hexanol were mixed to make a solution.…”
Section: Synthesis Of Snpmentioning
confidence: 99%
“…Previously, our group had applied sonochemical method for the synthesis of metal supported nanocomposites such as Au and Pt-based NP doped silica [19][20][21][22]. When ultrasound is irradiated in aqueous solution, the emitted energy reduce metal ions into metal NPs [23].…”
Section: Introductionmentioning
confidence: 99%
“…Our group applied the ultrasound irradiation method for the fabrication of metal-doped silica nanocomposites [8,11,23,24]. The acoustic cavitation phenomenon facilitates interparticle collision between metal and support material, inducing the binding between metal and support [25,26].…”
Section: Ultrasound-assisted Catalyst Synthesismentioning
confidence: 99%