Synthesis and crystal structure of a Schiff base derived from two similar pyrazolone rings and its rare earth complexes: DNA-binding and antioxidant activity

Wang, Mingfang; Zhou, Yang; Liu, Zeng-Chen; Li, Yong; Li, Tianrong; Yan, Mi-hui; Cheng, Xiao-ying

doi:10.1080/00958972.2012.727208

Cited by 19 publications

(3 citation statements)

References 46 publications

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“…This is due to the formation of thermally stable metal oxides, which results in the larger amount of residue weight loss in the complexes as compared to the SBL. The maximum amount of mass loss observed at higher temperatures in SBLYb than in the other complexes, which represents the ytterbium complex has better thermal stability compared with the erbium and praseodymium complexes 62 , 63 . The DTG curves of the SBL and its corresponding metal complexes are displayed in Fig.…”

Section: Resultsmentioning

confidence: 91%

“…For the metal complex-treated cells, the metal (Pr) and (Er) ions from SBLPr and SBLEr, respectively, cooperated with phosphorus moieties in DNA, causing to control the DNA reproduction, which resulted in the loss of cell viability and cell death 54 , 69 . It has been validated that SBLPr and SBLEr are active metal complexes against human cancer cell lines 55 , 62 . Omar et al .…”

Section: Resultsmentioning

confidence: 99%

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In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

Andiappan

Sanmugam

Easwaramoorthy

et al. 2018

Sci Rep

133

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A Schiff base ligand (SBL), N2, N3-bis (anthracen-9-ylmethylene) pyridine-2, 3-diamine, was synthesized through the condensation of 2,6-diaminopyridine and anthracene-9-carbaldehyde using a 1:2 ratio. 1H NMR spectra confirmed the observation of non-involvement aromatic carboxylic proton in SBL. A novel series of lanthanide (i.e., praseodymium (Pr), erbium (Er), and ytterbium (Yb))-based SBL metal complexes was successfully synthesized, and their functional groups were elaborately demonstrated using UV–visible, Fourier transform infrared (FT-IR), and fluorescence spectroscopy analyses. FT-IR spectral studies revealed that SBL behaved as a bidentate ligand and it was structured with metal ions by the two azomethine nitrogens. The synthesized SBL-based metal complexes were elaborately performed for cytotoxicity activity versus Vero, human breast cancer (MCF7), and cervical (HeLa) anticancer cell lines.

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Section: Resultsmentioning

confidence: 91%

Section: Resultsmentioning

confidence: 99%

In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

Andiappan

Sanmugam

Easwaramoorthy

et al. 2018

Sci Rep

133

View full text Add to dashboard Cite

show abstract

“…This may be attributed to the presence of a phenyl ring in the ligand that facilitates. Therefore, the complexes may be regarded as efficient intercalators of DNA [51][52][53] . and Eu 3+ complex exhibits characteristic luminescence of trivalent metal ions, which indicates that the ligand is a good organic chelator to absorb and transfer energy to metal ions.…”

Section: Mass Spectral Studiesmentioning

confidence: 99%

SYNTHESIS, CHARACTERIZATION, LUMINESCENCE AND DNA BINDING PROPERTIES OF Ln (III)-SCHIFF BASE FAMILY

Babu

Rao

Lee

2017

J. Chil. Chem. Soc.

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Pentadentate Schiff base ligand(N,N-bis(2-hydroxy-1-naphthylidene) diethylenetriamine) (H 2 L) that exhibits a N 3 O 2 donor set. Five rare earth complexes lanthanide (III), praseodymium (III), neodymium(III), samarium(III)and europium (III) complexes are synthesized and characterized based on elemental analyses, molar conductance, infrared, ultraviolet, thermo gravimetric, X-ray powder diffraction and mass spectral studies. Molar conductivity data suggests that the complexes are 1:1 electrolytics. Infrared spectral data suggest that the ligand binds through two naptholic oxygen atoms, two azomethine nitrogen atoms and one primary amine. IR studies reveal that the complexes contain both coordinating and ionic nitrate ligands. Thermal decomposition studies indicate the presence of two nitrate ions and two water molecules in the inner coordination sphere. Eu 3+ and Sm 3+ complexes exhibit luminescence properties. Further, the binding properties of these complexes with calf-thymus DNA have been investigated using absorption spectrophotometry.

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Two Lanthanide(III) Complexes based on the Schiff Base N,N′‐Bis(salicylidene)‐1,5‐diamino‐3‐oxapentane: Synthesis, Characterization, DNA‐binding Properties, and Antioxidation

Bai

Zhang

et al. 2014

Zeitschrift anorg allge chemie

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The Schiff base N,NЈ-bis(salicylidene)-1,5-diamino-3-oxapentane (H 2 L) and its lanthanide(III) complexes, PrL(NO 3 )(DMF)(H 2 O) (1) and Ho 2 L 2 (NO 3 ) 2 ·2H 2 O (2), were synthesized and characterized by physicochemical and spectroscopic methods. Single crystal X-ray structure analysis revealed that complex 1 is a discrete mononuclear species. The Pr III ion is nine-coordinate, forming a distorted capped square antiprismatic arrangement. Complex 2 is a centrosymmetric dinuclear neutral entity in which the Ho III ion is eight-coordinate with distorted square antiprismatic arrangement. The DNA-binding proper-

show abstract

Synthesis and crystal structure of a Schiff base derived from two similar pyrazolone rings and its rare earth complexes: DNA-binding and antioxidant activity

Cited by 19 publications

References 46 publications

In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

In vitro cytotoxicity activity of novel Schiff base ligand–lanthanide complexes

SYNTHESIS, CHARACTERIZATION, LUMINESCENCE AND DNA BINDING PROPERTIES OF Ln (III)-SCHIFF BASE FAMILY

Two Lanthanide(III) Complexes based on the Schiff Base N,N′‐Bis(salicylidene)‐1,5‐diamino‐3‐oxapentane: Synthesis, Characterization, DNA‐binding Properties, and Antioxidation

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