Synthesis and Crystallization of Poly(butylenes succinate-block-butylene sebacate)

Abstract

A series of aliphatic biodegradable poly (butylene succinate-block-butylene sebacate) (PBSuBSe) copolyesters were synthesized by incorporation of PBSe into the PBSu molecular chains. The molecular weight, crystallization behaviors and the crystal structure of the copolyesters were investigated by using gel permeation chromatography (GPC), differential scanning calorimetry (DSC) and wide angle X-ray diffraction (WAXD), respectively. The copolyesters might be potentially useful as the biodegradable materials.

Synthesis, Characterization and Cytotoxicity of Certain Peg400 Based Biodegradable Aliphatic Copolyesters

“…But with the presence of transesterification catalysts, high molecular weight polyesters are obtained with improved mechanical properties 4 . In general, high molecular weight polymers require a longer time to attain equilibrium 6,7 . Polyethylene glycol (PEG) is one of the polymers that is been widely accepted by food and drug administration (FDA), as the most biocompatible polymers for internal consumption 8,9 .…”

"Synthesis, Characterization and Comparison of Biodegradable Aliphatic Copolyesters: Poly Ethylene Glycol Octanediol Sebacate and Polyethylene Glycol Dodecanediol Adipate"

“…PEG is a polyether which contains an oxygen atom as the polymer backbone and it interacts with cell membranes but is very harmful to active proteins and cells 7 . PEG helps in diminishing the collection of red blood cells and enhances the biocompatibility of PEG copolymers that are embedded as cardiovascular gadgets, for example, stents 8,9 . Reports declare that, this is the most utilized polymer in the biomedical field of drug delivery and the main remedial specialist that has a market endorsement for various drugs 10,11 .…”